Could a breathing machine help kids with severe asthma avoid the ICU?

NCT ID NCT07582211

Recruiting now Symptom relief Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This study tests whether giving children aged 5-17 with severe asthma attacks early breathing support (called BPAP) in the emergency room is practical and safe. About 36 children will either get standard asthma care alone or standard care plus BPAP. The goal is to see if this approach can be studied in a larger trial and whether it might improve breathing and reduce the need for intensive care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bilevel positive airway pressure (BPAP) device
What this could lead to: If this works, it could show that early BPAP breathing support helps children with severe asthma attacks recover faster and avoid intensive care.
What could go wrong: This is a very small, early feasibility study with only 36 children. It is not designed to prove effectiveness, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute asthma childhood onset asthma status asthmaticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ASTHMA BIPAP NON-INVASIVE POSITIVE PRESSURE VENTILATION PEDIATRIC ASTHMA

Contacts and locations

Locations

Children's Hospital of Philadelphia
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States
Nationwide Children's Hospital
NOT_YET_RECRUITING

Columbus, Ohio, 43205, United States

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