Acute asthma
MONDO:0850283An asthma that is characterized by severe and sudden onset of increasing wheezing, airways closing, smooth muscle contraction, mucus plugging and lower airway edema that may be reversible upon treatment.
38 clinical trials for this condition and its sub-types.
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Broader categories
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Could a higher dose of an old asthma drug help kids breathe easier in an emergency?
Disease control CompletedThis study tests whether a high dose of montelukast (Singulair), given by mouth, can help children aged 4 to 12 who are in the hospital with a moderate or severe asthma attack. The goal is to find the best dose for a future larger study. Children receive either the high-dose mont…
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Dietary supplement shows promise for controlling kids' asthma and allergy symptoms
Disease control CompletedThis study tested a dietary supplement containing immune-supporting nutrients and postbiotics in 40 children aged 5–12 with asthma and/or allergic rhinitis. The goal was to see if the supplement could improve symptom control over 6 months. Researchers also looked at changes in im…
Phase: NA • Sponsor: Federico II University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Rural patients get Hospital-Level care at home in landmark trial
Disease control CompletedThis study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Could ambulance asthma treatment keep kids out of the hospital?
Symptom relief CompletedThis pilot study tested whether giving two asthma medications (ipratropium and dexamethasone) to children during ambulance transport can reduce hospital admissions. The study included 44 children aged 2 to 17 with severe wheezing. The goal was to see if this early treatment is fe…
Phase: PHASE2 • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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One shot vs three days: which steroid wins for Kids' asthma?
Symptom relief CompletedThis study compared a single IV dose of dexamethasone to three days of oral prednisolone for treating acute asthma attacks in children aged 2 to 12. A total of 224 children participated, and the severity of their asthma was measured using a standard score. The goal was to see if …
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New study reveals hidden dangers of severe asthma in kids
Knowledge-focused CompletedThis study tracked 60 children aged 5 to 15 who survived a near fatal asthma attack in the UK and Ireland. Researchers collected data on risk factors, medical care, and social and environmental influences. The goal is to create better care guidelines and reduce future risks.
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC