Could a common antibiotic tame severe asthma in kids?

NCT ID NCT06223828

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether azithromycin, an antibiotic, can reduce airway inflammation in children ages 3-17 hospitalized for critical asthma. One hundred participants will receive the drug for three days while researchers monitor inflammation markers and side effects. The goal is to see if this treatment can shorten ICU stays and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

azithromycin (an antibiotic that may also reduce inflammation)

What this could lead to

If it works, this could offer a short, safe treatment to help children recover faster from severe asthma attacks and reduce time in the ICU.

What could go wrong

This is an early-phase, open-label study with no placebo group, so results may be less reliable. Azithromycin can cause side effects like stomach upset or heart rhythm changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute asthma childhood onset asthma Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins All Children's Hospital

    RECRUITING

    St. Petersburg, Florida, 33701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••