AI may predict transfusion needs to shield ICU patients from organ failure
NCT ID NCT07762131
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study is testing whether an artificial intelligence model can predict which critically ill patients in the intensive care unit (ICU) are at risk of developing multiple organ dysfunction syndrome (MODS), a serious complication where two or more organs fail. Researchers will collect data from about 2,600 adult ICU patients, including lab results, vital signs, and transfusion details, to build and validate the AI model. The goal is to help doctors make more precise transfusion decisions, potentially reducing organ failure and improving outcomes. This is an observational study, meaning no treatments are assigned—the AI model is being developed and tested using existing patient data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Red blood cell transfusion exposure (observational, no intervention)
- What this could lead to
- If successful, this could lead to a personalized transfusion decision-support tool that helps doctors reduce organ failure and improve survival in ICU patients.
- What could go wrong
- This is an observational study, so it can only find associations, not prove cause and effect. The AI model may not work perfectly in all hospitals or patient groups.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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