A hidden clue in the fingertips: could a pulse oximeter reading forecast sepsis outcomes?

NCT ID NCT07740304

Recruiting now Knowledge-focused Sponsor: Trakya University Source: ClinicalTrials.gov ↗

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study asks whether a simple, non-invasive reading from a standard pulse oximeter—the perfusion index—can help predict survival in people with sepsis or septic shock. Sepsis can impair blood flow to small vessels even when blood pressure looks normal, and this 'hidden' poor perfusion may be linked to worse outcomes. Researchers will track how the perfusion index changes over the first 24 hours in the ICU and see if it can predict death within 28 days, alongside other bedside measures. The study involves 400 adults across two centers and requires no extra procedures or changes to care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the perfusion index proves reliable, it could give doctors a simple, non-invasive tool to spot hidden poor blood flow and better predict outcomes in sepsis patients.
What could go wrong: This is an observational study, so it can't prove cause and effect. The findings may not apply to all sepsis patients, and the perfusion index might not add much beyond existing tools.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CRITICAL ILLNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Critical Illness infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS SEPSIS

Contacts and locations

Locations

Trakya University Faculty of Medicine, Department of Internal Medicine, Division of Intensive Care Medicine
RECRUITING

Edirne, Merkez, 22130, Turkey (Türkiye)
Uzunköprü State Hospital, Intensive Care Unit
NOT_YET_RECRUITING

Edirne, Uzunköprü, 22200, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.