Could a simple injection tame stubborn achilles pain?

NCT ID NCT07650396

Recruiting now Disease control Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether adding up to three corticosteroid injections to standard exercise therapy improves pain and function in adults with chronic midportion Achilles tendinopathy. Participants receive either the steroid injection or a placebo (lidocaine only), alongside education and a structured calf-strengthening program. The study tracks symptom changes and any tendon ruptures over one year to weigh benefits against risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Methylprednisolone acetate (corticosteroid) plus lidocaine
What this could lead to: If successful, adding a few corticosteroid injections to exercise therapy could provide lasting pain relief and better function for people with stubborn Achilles tendon pain.
What could go wrong: This is a phase 3 trial, but corticosteroid injections carry a risk of tendon rupture. The study directly measures this risk, and results may not apply to all types of Achilles problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

disease of the tendon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACHILLES TENDINOPATHY (AT)

Contacts and locations

Locations

Erasmus MC
RECRUITING

Rotterdam, Netherlands

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