CtDNA test guides chemo to stop rectal cancer return

NCT ID NCT07188025

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people who have a positive ctDNA blood test (a sign of leftover cancer cells). About 103 adults with high-risk rectal cancer will either receive chemo or be observed. The goal is to see if chemo improves how long people stay cancer-free.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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  • Contact

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Locations

  • Admiraal De Ruyter Ziekenhuis

    RECRUITING

    Goes, Netherlands

    Contact

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  • Albert Schweitzer Ziekenhuis

    RECRUITING

    Dordrecht, Netherlands

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  • Amphia

    RECRUITING

    Breda, Netherlands

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  • Amsterdam UMC

    NOT_YET_RECRUITING

    Amsterdam, Netherlands

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  • Antonius Ziekenhuis Sneek

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    Sneek, Netherlands

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  • Bernhoven

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    Uden, Netherlands

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  • Bravis Ziekenhuis

    RECRUITING

    Roosendaal, Netherlands

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  • Canisius Wilhelmina Ziekenhuis

    NOT_YET_RECRUITING

    Nijmegen, Netherlands

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  • Catharina Ziekenhuis

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    Eindhoven, Netherlands

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  • Dijklander Ziekenhuis

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    Hoorn, Netherlands

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  • Elisabeth-Tweesteden Ziekenhuis

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    Tilburg, Netherlands

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  • Erasmus MC

    RECRUITING

    Rotterdam, Netherlands

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  • Franciscus

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    Rotterdam, Netherlands

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  • Frisius MC

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    Leeuwarden, Netherlands

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  • Haaglanden Medisch Centrum

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    The Hague, Netherlands

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  • Ikazia Ziekenhuis

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    Rotterdam, Netherlands

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  • Jeroen Bosch Ziekenhuis

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    's-Hertogenbosch, Netherlands

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  • Leids Universitair Medisch Centrum (LUMC)

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    Leiden, Netherlands

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  • Maasstad Ziekenhuis

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    Rotterdam, Netherlands

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  • Martini Ziekenhuis

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    Groningen, Netherlands

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  • Meander Medisch Centrum

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    Amersfoort, Netherlands

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  • Radboud Universitair Medisch Centrum

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    Nijmegen, Netherlands

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  • Reinier de Graaf Ziekenhuis

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    Delft, Netherlands

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  • Ziekenhuisgroep Twente

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    Almelo, Netherlands

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  • ZorgSaam

    RECRUITING

    Terneuzen, Netherlands

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