CtDNA test guides chemo to stop rectal cancer return
NCT ID NCT07188025
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people who have a positive ctDNA blood test (a sign of leftover cancer cells). About 103 adults with high-risk rectal cancer will either receive chemo or be observed. The goal is to see if chemo improves how long people stay cancer-free.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Admiraal De Ruyter Ziekenhuis
RECRUITINGGoes, Netherlands
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Albert Schweitzer Ziekenhuis
RECRUITINGDordrecht, Netherlands
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Amphia
RECRUITINGBreda, Netherlands
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Amsterdam UMC
NOT_YET_RECRUITINGAmsterdam, Netherlands
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Antonius Ziekenhuis Sneek
NOT_YET_RECRUITINGSneek, Netherlands
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Bernhoven
NOT_YET_RECRUITINGUden, Netherlands
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Bravis Ziekenhuis
RECRUITINGRoosendaal, Netherlands
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Canisius Wilhelmina Ziekenhuis
NOT_YET_RECRUITINGNijmegen, Netherlands
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Catharina Ziekenhuis
NOT_YET_RECRUITINGEindhoven, Netherlands
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Dijklander Ziekenhuis
NOT_YET_RECRUITINGHoorn, Netherlands
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Elisabeth-Tweesteden Ziekenhuis
RECRUITINGTilburg, Netherlands
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Erasmus MC
RECRUITINGRotterdam, Netherlands
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Franciscus
RECRUITINGRotterdam, Netherlands
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Frisius MC
NOT_YET_RECRUITINGLeeuwarden, Netherlands
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Haaglanden Medisch Centrum
NOT_YET_RECRUITINGThe Hague, Netherlands
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Ikazia Ziekenhuis
RECRUITINGRotterdam, Netherlands
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Jeroen Bosch Ziekenhuis
RECRUITING's-Hertogenbosch, Netherlands
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Leids Universitair Medisch Centrum (LUMC)
NOT_YET_RECRUITINGLeiden, Netherlands
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Maasstad Ziekenhuis
RECRUITINGRotterdam, Netherlands
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Martini Ziekenhuis
RECRUITINGGroningen, Netherlands
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Meander Medisch Centrum
RECRUITINGAmersfoort, Netherlands
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Radboud Universitair Medisch Centrum
RECRUITINGNijmegen, Netherlands
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Reinier de Graaf Ziekenhuis
RECRUITINGDelft, Netherlands
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Ziekenhuisgroep Twente
NOT_YET_RECRUITINGAlmelo, Netherlands
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ZorgSaam
RECRUITINGTerneuzen, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can AI learn to grade endoscopy quality from video?
- Can precision protons spare rectal cancer patients from harsh side effects?
- A new radiation combo may spare the rectum in early cancer