Erasmus Medical Center

This trial aims to find a functional cure for HIV by using a combination of three existing drugs to 'shock' the hidden, dormant virus out of hiding so the immune system can 'kill' it. It will involve 30 adults with well-controlled HIV. The study first tests single doses for safet…

This study is testing whether giving intravenous nutrition directly during dialysis treatments can help patients build muscle and better control blood pressure. It involves 16 adults who have been on long-term dialysis and are at risk for malnutrition. Researchers will compare we…

This study aims to find out which of two commonly used medications works better for treating frontal fibrosing alopecia, a type of permanent scarring hair loss that mostly affects women. Fifty adult patients will choose to take either hydroxychloroquine or methotrexate and be fol…

This study is testing whether a custom 3D-printed device can make radiation treatment for advanced cervical cancer more precise and effective. Twenty-five patients will receive their standard radiation treatment, but for one session, doctors will use this new, personalized applic…

This study is testing a new, more precise radiation technique to treat kidney tumors. The goal is to deliver radiation that destroys the tumor while minimizing damage to the healthy part of the kidney, which could help preserve kidney function. The research will enroll 40 patient…

This study is testing whether giving chemotherapy after surgery can prevent rectal cancer from returning in patients who are at high risk. Researchers will use a special blood test to identify patients who have tiny amounts of cancer DNA left after their operation. About 103 pati…

This study is testing a new computer tool that helps doctors decide when a patient is ready to start moving and planning to go home after major surgery for cancer or gastrointestinal issues. The tool analyzes the patient's routine hospital data and gives a simple 'yes' or 'no' su…

This study aims to see if a newer, gentler bone-cutting tool called piezosurgery leads to better results than standard tools for corrective jaw surgery. Researchers will compare the two techniques in 70 adults to see if the newer method causes less nerve damage, reduces bleeding,…

This study is testing an improved ultrasound method to check if bile duct cancer has spread to nearby lymph nodes before surgery. It will observe 250 patients to see if this better scan can accurately identify patients who should not undergo a major operation because the cancer h…

This study aims to create a better prediction tool to estimate the risk of a liver transplant failing within 90 days after surgery. Researchers will analyze data from 3,000 living donors and recipients in an international registry to test existing prediction models and build a ne…

This study aims to understand how measles infection affects children's immune systems long-term. Researchers will compare 100 children, some vaccinated and some not, to see if measles causes 'immune amnesia' - where the body forgets how to fight other infections. The study will m…

This study asks ICU nurses to compare new dialysis bags with the ones currently used for continuous kidney replacement therapy. About 126 experienced nurses will complete surveys before and after trying the new bags, rating them on ease of use, safety, and efficiency. The goal is…