Erasmus Medical Center

This study tests a new, custom-made 3D-printed applicator for delivering high-dose radiation (brachytherapy) to treat locally advanced cervical cancer. About 25 participants will receive the treatment to see if the device works safely and as planned. The goal is to improve how ra…

This early-stage trial tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and then help the immune system eliminate those infected cells. The goal is a 'functional cure' where the virus is c…

This study looks at whether giving extra nutrition during dialysis sessions helps people on long-term hemodialysis build muscle and manage blood pressure. Researchers will compare the effects of this special nutrition with usual care in 16 adults who have been on dialysis for at …

This study compares two medicines, hydroxychloroquine and methotrexate, to see which works better for frontal fibrosing alopecia, a type of scarring hair loss that mainly affects women. About 50 adults who choose to start one of these treatments will be followed for up to 48 week…

This study compares a new ultrasonic cutting tool (piezosurgery) to standard saws and drills for jaw realignment surgery. The goal is to see if it reduces nerve damage and other complications. About 70 adults will take part, and their recovery will be tracked for one year.

This observational study will analyze data from 110 mechanically ventilated patients to understand how often their breathing is out of sync with the ventilator. Researchers will use special software to detect these mismatches and see if they relate to patient outcomes. The goal i…

This study tests whether an instructional video about medication management can reduce errors in kidney transplant patients compared to standard verbal instructions. About 308 adult patients at Erasmus MC will be randomly assigned to watch the video or receive usual teaching. Res…

This study looks at how a diet high in acid-forming foods (like meat, cheese, and grains) affects kidney function and blood sugar in people with type 2 diabetes and chronic kidney disease. Researchers will ask 80 participants to follow either a high- or low-acid diet for 8 weeks …

This study asks 126 ICU nurses to compare new dialysis bags with current ones used for continuous kidney replacement therapy. Nurses will fill out surveys before and after using the new bags, rating them on ease of use, safety, and efficiency. The goal is to see if the new design…

After gastrointestinal or cancer surgery, it's hard to know when it's safe to start rehabilitation. This study tests an AI tool that analyzes hospital data to predict which patients are ready for early rehab. The tool gives a simple yes/no answer to help doctors decide. The study…

This study will analyze data from 3,000 living liver donors and their recipients to create a more accurate prediction model for early graft failure after living donor liver transplantation. Researchers will also test how well existing prediction models work. The goal is to give d…

This study looks at 100 children to understand why measles causes short-term immune suppression but also lifelong immunity. Researchers will measure antibodies and immune cells before and after infection to see how measles changes the body's immune memory. The goal is to solve th…

This study looks at whether an improved endoscopic ultrasound (EUS) can better find cancer in lymph nodes of people with bile duct cancer. About 250 patients with presumed resectable cancer will get the enhanced EUS before surgery. The goal is to see how many patients are spared …