New cocktail aims to flush out and destroy hidden HIV
NCT ID NCT07384624
First seen Feb 03, 2026 · Last updated May 05, 2026 · Updated 11 times
Summary
This early-stage trial tests whether a combination of three existing drugs (topiramate, lenalidomide, and pyrimethamine) can wake up dormant HIV hiding in the body and then help the immune system eliminate those infected cells. The goal is to reduce the hidden HIV reservoir, moving toward a functional cure where the virus stays under control without lifelong medication. The study involves 30 adults with well-controlled HIV who are on standard antiretroviral therapy.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Amsterdam University Medical Center
Amsterdam, Netherlands
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Erasmus MC
Rotterdam, Netherlands
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Radboud University Medical Center
Nijmegen, Netherlands
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University Medical Center Utrecht
Utrecht, Netherlands
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Conditions
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