Olive oil as a shield? trial tests whether a daily spoonful cuts heart risks in HIV
NCT ID NCT07761819
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial asks whether taking 50 mL of extra virgin olive oil every day can reduce the chance of heart attacks, strokes, and related deaths in people living with HIV. About 1,300 adults aged 50–75 with well-controlled HIV and at least one heart risk factor will be randomly assigned to add olive oil to their diet or to continue their usual eating habits. Over five years, researchers will compare how many in each group experience a major cardiovascular event, and also track changes in weight, blood pressure, and other health markers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Extra virgin olive oil (EVOO) taken daily as a dietary supplement
- What this could lead to
- If it works, daily olive oil could become a simple, low-cost way to lower heart and stroke risk in people living with HIV.
- What could go wrong
- This is an open-label trial, so results may be influenced by expectations. The effect may be modest, and daily intake of 50 mL adds calories, which could affect weight.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Universitario Costa del Sol
Marbella, Málaga, 29603, Spain
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