HIV - HUMAN IMMUNODEFICIENCY VIRUS

This study tests whether resmetirom, a drug already approved for another liver condition, can safely reduce liver fat in people with HIV who also have fatty liver disease (MASLD). About 120 adults with well-controlled HIV will take either resmetirom or a placebo daily for 24 week…

This study tests whether empagliflozin, a diabetes drug, can help people with HIV who are overweight or obese lose weight and improve metabolic health. Researchers will enroll 66 adults with HIV who are on a specific antiretroviral therapy and have a BMI over 30. Participants wil…

This study tests whether two experimental antibodies (MGD014 and MGD020) are safe in people with HIV who are on standard antiretroviral therapy. Some participants also receive a drug called Vorinostat to help expose hidden HIV, or temporarily stop their regular HIV meds. The goal…

This study tests whether measuring HIV drugs in hair can reliably show if patients are taking their medication as prescribed. Researchers will collect hair and blood samples from 30 HIV patients who are known to be compliant. The goal is to see if hair can be a simple, non-invasi…

This study looks at whether giving HIV prevention pills (PrEP) at the same time as opioid addiction treatment in pharmacies is practical and acceptable. About 350 HIV-negative adults on opioid therapy in Alberta and Saskatchewan will take part. Researchers will track how many peo…

This study tests two types of smell training in 80 adults aged 40+ with HIV. Participants will sniff scents at home twice a day for 8 weeks. The goal is to see if the training is easy to do and if it improves smell and thinking abilities.

This study tests a program called TransAction to help transgender women in Ho Chi Minh City improve their HIV prevention and care. 80 participants will either join the full program (individual sessions, group support, and social events) or just social events. The goal is to see i…

This study looks at whether traditional healers in rural Uganda can offer HIV screening tests to children aged 18 months to 5 years. Researchers will compare how many caregivers accept testing from a healer versus how many follow a referral to a health center. The goal is to find…

This study looks at whether people with tuberculosis (TB) who have no symptoms can still pass the infection to others. Researchers will follow about 6,770 participants, including those with HIV, and use advanced genetic testing to track TB spread among close contacts. The goal is…