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Heart attack aftermath: which treatment causes less internal bleeding?

NCT ID NCT03677466

Completed Knowledge-focused Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined bleeding inside the heart muscle (intramyocardial hemorrhage) in 60 patients who had a severe type of heart attack called STEMI. Researchers compared two treatment strategies: giving clot-busting drugs followed by a procedure to open the artery, versus going straight to the artery-opening procedure. They used MRI scans to measure bleeding and heart function. The goal was to understand which approach might lead to better recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fibrinolytic drugs (Tenecteplase, Alteplase, Streptokinase) and PCI procedure
What this could lead to
If successful, this could help doctors choose the best treatment strategy to reduce heart muscle bleeding after a heart attack, potentially improving recovery.
What could go wrong
This was a small, observational study with only 60 participants, so results may not apply to everyone. It did not test a new treatment, only compared existing ones.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOCARDIAL INFARCTION MYOCARDIAL INJURY MYOCARDIAL NECROSIS STEMI

Contacts and locations

Locations

  • Cardiology Research Institute

    Tomsk, 634012, Russia

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