Heart attack aftermath: which treatment causes less internal bleeding?
NCT ID NCT03677466
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined bleeding inside the heart muscle (intramyocardial hemorrhage) in 60 patients who had a severe type of heart attack called STEMI. Researchers compared two treatment strategies: giving clot-busting drugs followed by a procedure to open the artery, versus going straight to the artery-opening procedure. They used MRI scans to measure bleeding and heart function. The goal was to understand which approach might lead to better recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fibrinolytic drugs (Tenecteplase, Alteplase, Streptokinase) and PCI procedure
What this could lead to
If successful, this could help doctors choose the best treatment strategy to reduce heart muscle bleeding after a heart attack, potentially improving recovery.
What could go wrong
This was a small, observational study with only 60 participants, so results may not apply to everyone. It did not test a new treatment, only compared existing ones.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cardiology Research Institute
Tomsk, 634012, Russia