Heart attack diagnosis gets a Sex-Specific upgrade: new study tests fairer troponin cutoffs

NCT ID NCT05336435

First seen May 21, 2026 · Last updated May 21, 2026

Summary

This study looked at whether using different blood test thresholds for men and women can help doctors more accurately diagnose heart attacks. Current tests use the same cutoff for everyone, but healthy women naturally have lower troponin levels than men, which may lead to missed heart attacks in women. The trial involved nearly 5,000 patients across 22 Danish hospitals and compared the new sex-specific cutoffs to the standard approach. The goal was to see if this change leads to better treatment and fewer future heart problems for both sexes.

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Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, 9000, Denmark

  • Aarhus University Hospital

    Aarhus, 8000, Denmark

  • Amager & Hvidovre Hospital

    Hvidovre, 2650, Denmark

  • Bispebjerg & Frederiksberg Hospital

    Bispebjerg, 2400, Denmark

  • C Torp-Pedersen

    Hillerød, 3400, Denmark

  • Central Jutland Regional Hospital (Viborg Hospital & Silkeborg Hospital)

    Viborg, 8800, Denmark

  • Glostrup University Hospital

    Glostrup Municipality, 2600, Denmark

  • Gødstrup Regional Hospital

    Gødstrup, 7400, Denmark

  • Herlev & Gentofte Hospital

    Herlev, 2730, Denmark

  • Holbaek Sygehus

    Holbæk, 4300, Denmark

  • Horsens Hospital

    Horsens, 8700, Denmark

  • Hospital of Southern Jutland

    Aabenraa, 6200, Denmark

  • North Denmark Regional Hospital

    Hjørring, 9800, Denmark

  • Nykøbing Falster County Hospital

    Nykøbing Falster, 4800, Denmark

  • Odense University Hospital

    Odense, 5000, Denmark

  • Randers Regional Hospital

    Randers, 8930, Denmark

  • Rigshospitalet (Blegdamsvej)

    Copenhagen Ø, 2100, Denmark

  • Slagelse Sygehus

    Slagelse, 4200, Denmark

  • Svendborg Hospital

    Svendborg, 5700, Denmark

  • Sydvestjysk Sygehus

    Esbjerg, 6700, Denmark

  • Sygehus Lillebælt (Kolding Sygehus & Vejle Sygehus)

    Kolding, 6000, Denmark

  • Zealand University Hospital

    Køge, 4600, Denmark

Conditions

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