Emotional stress may be a hidden trigger for repeat heart attacks — a study investigates

NCT ID NCT04123197

Completed Knowledge-focused Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study looks at how mental stress affects the heart in men and women who have had a heart attack within the past 8 months. Participants undergo a stress challenge and are followed for up to 3 years to see if stress-induced changes in the heart are linked to future heart problems. The goal is to understand sex differences and the mechanisms behind emotional stress and heart disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the link between emotional stress and heart problems is better understood, it could lead to new ways to prevent repeat heart attacks.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test any therapy. Results may show associations but not prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOCARDIAL INFARCTION

Contacts and locations

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Locations

Emory University Hospital

Atlanta, Georgia, 30322, United States
Grady Health System

Atlanta, Georgia, 30322, United States
The Emory Clinic

Atlanta, Georgia, 30322, United States

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