Stem cell infusion aims to repair hearts after attack

NCT ID NCT00877903

Completed Disease control Sponsor: Mesoblast, Inc. Source: ClinicalTrials.gov ↗

First seen Mar 11, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the past week. The goal was to see if the stem cells could safely improve heart function and reduce damage. Participants were randomly assigned to receive either the stem cells or a placebo, and their heart health was tracked for several months.

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Contacts and locations

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Locations

Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Austin Heart P.A.

Austin, Texas, 78756, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Cotton-O'Neil Clinical Research Center

Topeka, Kansas, 66604, United States
Drexel University College of Medicine

Philadelphia, Pennsylvania, 19102, United States
Fletcher Allen Health Care

Burlington, Vermont, 05401, United States
McGill University Health Centre

Montreal, Quebec, H3A 1A1, Canada
Mercy Gilbert Medical Center / Catholic Health Care West

Gilbert, Arizona, 85297, United States
Michigan Cardiovascular Institute

Saginaw, Michigan, 48601, United States
Minneapolis Heart Institute

Minneapolis, Minnesota, 55407, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
Oregon Health & Science University

Portland, Oregon, 97239, United States
Penn State University - Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
The Care Group

Indianapolis, Indiana, 46290, United States
The Lindner Research Center

Cincinnati, Ohio, 45219, United States
The Ohio State University Medical Center

Columbus, Ohio, 43210, United States
The Stern Cardiovascular Center

Germantown, Tennessee, 38138, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
UC Davis Medical Center

Sacramento, California, 95817, United States
UMDNJ - Robert Wood Johnson Medical School

New Brunswick, New Jersey, 08903, United States
UMass Memorial Medical Center

Worcester, Massachusetts, 01655, United States
University at Buffalo - Buffalo General Hospital

Buffalo, New York, 14203, United States
University of Arizona

Tucson, Arizona, 85724, United States
University of California - San Diego (UCSD)

San Diego, California, 92103, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
University of Maryland Hospital

Baltimore, Maryland, 21201, United States
University of Miami

Miami, Florida, 33136, United States
University of Texas Health Science Center

Houston, Texas, 77030, United States
University of Wisconsin School of Medicine

Madison, Wisconsin, 53792, United States
Wake Forest University School of Medicine

Winston-Salem, North Carolina, 27157, United States
William Beaumont Hospital

Royal Oak, Michigan, 48073, United States

Conditions

Explore the condition pages connected to this study.

MYOCARDIAL INFARCTION