Could a natural compound in food help aging hearts?
NCT ID NCT06186102
First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 5 times
Summary
This study tests whether spermidine, a natural substance found in foods like soy and aged cheese, can improve heart and muscle health in elderly people with coronary artery disease. 180 participants aged 65 and older will receive either spermidine capsules or a placebo for a period. Researchers will measure changes in heart mass, muscle mass, inflammation, and exercise capacity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Spermidine (a dietary supplement)
- What this could lead to
- If it works, this could point toward a simple supplement to help elderly heart patients maintain heart and muscle function.
- What could go wrong
- This is a small, early-phase trial (180 people) testing a supplement, not a drug. Results may not lead to a proven treatment, and benefits may be modest or absent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aarhus University Hospital
Aarhus, Jutland, 8200, Denmark
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