QUALITY OF LIFE

This study is testing whether a minimally invasive procedure called alcohol sclerotherapy can better control painful symptoms and improve quality of life for women with ovarian endometriomas. Researchers will compare the procedure, which involves using ultrasound to guide an alco…

This study compares two ways of delivering targeted radiation to control a small number of cancer tumors that have spread. It aims to see if a single, high-dose treatment is as safe and effective as spreading the same total dose over several sessions. The research will measure si…

This study is testing a new, personalized follow-up program for people who have been treated for early-stage colon or rectal cancer. The program uses a smartphone app and blood tests to monitor for cancer recurrence and help manage long-term side effects like anxiety, fatigue, an…

This study aims to see if a combination of early high-protein feeding and muscle stimulation can help prevent severe muscle loss in patients who are critically ill in the Intensive Care Unit (ICU). It will involve 40 patients, with half receiving the special combination therapy a…

This study is testing whether a smartphone app can help older African Americans better manage their high blood pressure. Researchers want to see if using the app for reminders and support helps people take their medications more consistently and improves their blood pressure read…

This study is testing a non-surgical radiation treatment for people with severe hand tremor from Essential Tremor or Parkinson's disease. It aims to see if this one-time, outpatient procedure improves patients' quality of life and reduces shaking. Participants will complete quest…

This study is testing a new treatment approach for patients with a type of esophageal cancer that can be surgically removed. Before surgery, patients receive a combination of a newer immunotherapy drug (adebrelimab) and standard chemotherapy. The main goal is to see if this pre-s…

This study compares three common, non-surgical ways to correct nearsightedness in children and teens: special 'defocus' glasses, regular glasses, and overnight contact lenses (orthokeratology). Researchers will follow 90 kids for one year to see which method works best, how it af…

This study is testing whether a standard two-drug inhaler for COPD can improve not just breathing, but also heart function and overall quality of life. It will involve 80 adults newly diagnosed with moderate-to-severe COPD. Researchers will measure changes in exercise capacity, h…

This study is testing if using a positive airway pressure (PAP) machine at night helps older veterans who have both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea. Researchers want to see if the machine reduces daytime sleepiness, improves sleep quality …

This study is testing a special suction dressing (Negative Pressure Wound Therapy) to see if it helps prevent wound problems after emergency abdominal surgery. Researchers will compare it against regular dressings in 720 adults. The goal is to reduce infections, wound openings, f…

This study is testing a digital app called 'EmpowerMyCH' designed to help adults with congenital heart disease better manage their health. The app includes features like a digital medical record, health information, and community support. Researchers want to see if using the app …

This study is testing whether installing special air cleaners or ventilators in homes can improve air quality and help people with asthma breathe easier. Researchers will compare real devices to fake ones in 80 low-income households in Texas over two years. They will measure air …

This large trial is testing if a single dose of a common antibiotic, given soon after a brain-injured patient is put on a breathing machine, can prevent dangerous lung infections (pneumonia). The goal is to see if preventing these infections helps patients survive and recover bet…

This study is testing whether a smartphone-based coaching program can help people in rural areas better manage their high blood pressure. About 334 participants with uncontrolled blood pressure will use home monitors and receive either personalized coaching or general health info…

This study compares two different approaches to ovarian stimulation during IVF treatment. Women undergoing either elective egg freezing or IVF with genetic testing will try both treatment methods to see which one they find more tolerable and satisfying. Researchers will measure q…

This study is testing whether combining two existing home-based care programs can help homebound older adults who feel lonely or isolated. The program, called CAPABLE, involves visits from an occupational therapist, a nurse, and a handyman over four months to help people perform …

This study is testing whether giving extra support and training to case managers helps them better use a structured care plan for veterans. The plan focuses on managing pain and risky substance use, especially for veterans who have recently left military service. Researchers want…

This study is testing a home-based support program for people waiting for a kidney transplant who are currently 'inactive' on the official waitlist. A team of a nurse, an occupational therapist, and a handyman will visit participants at home over four months to help them tackle p…

This study is testing whether low-cost home improvements and practical advice can protect people's health during extreme heat in crowded, low-income neighborhoods of Karachi, Pakistan. Researchers will work with over 7,000 households to see if simple changes like adding shade, pa…

This study is testing whether simple, low-cost home improvements like reflective roof paint, added shade, and better airflow can protect people's health during extreme heat in rural Pakistan. Researchers will compare villages that receive these cooling interventions and heat safe…

This study is testing whether a handheld breathing device called an OPEP can improve the day-to-day quality of life for people with bronchiectasis, a chronic lung condition. It will involve 60 children (aged 8+) and adults who are not currently using this type of device. Research…

This study is testing whether a personalized exercise program can help lymphoma and breast cancer patients maintain their physical fitness, heart function, and quality of life during cancer treatment. Researchers will compare two approaches: one group will follow a structured phy…

This study is testing if using the Headspace mindfulness app can help women with endometrial or cervical cancer feel less stressed and have a better quality of life during their cancer treatment. Researchers want to see if practicing mindfulness with the app can also help reduce …

This study is testing two minimally invasive procedures to control severe chest pain in adults who have suffered combat-related chest injuries in Ukraine. It aims to see if using extreme cold (cryoablation) or controlled heat (radiofrequency ablation) on specific nerves is better…

This study is testing if a 12-week digital yoga program called MediYoga can improve quality of life for people with a common heart rhythm problem called atrial fibrillation (AF). Researchers will enroll 456 participants with AF to see if doing gentle yoga, deep breathing, and med…

This study is testing a mobile phone app called Stappvoorstap, designed to help adults manage stress while they wait to start mental health treatment. The app helps users track daily stress, learn their personal patterns, and provides coping strategies and relaxation exercises. R…

This study aims to see if exercising underwater is better than regular aerobic exercise for improving muscle power and quality of life. It will involve 100 women aged 16-50 who have low muscle strength, general fatigue, and a lower quality of life. Researchers will measure pain, …

This study is testing a new rehabilitation program that uses multiple senses to help people with profound vision loss. Researchers want to see if combining vision, hearing, and hand coordination training can improve daily function and quality of life. The program is designed for …

This study is testing whether adding a specific set of head and body exercises (Brandt-Daroff) to a standard vertigo treatment (GANS maneuver) works better to reduce dizziness and improve daily life for people with Benign Paroxysmal Positional Vertigo (BPPV). Researchers will rec…

This study aims to see if using a robotic system to perform sleeve gastrectomy (a common weight loss surgery) causes less pain right after surgery compared to the standard laparoscopic (keyhole) method. It will involve 91 patients at the Cleveland Clinic who are eligible for this…

This study is testing a wellness program called 'Green Oasis' to see if it improves quality of life and happiness for people living in a transitional housing community. About 50 residents will take part in activities like light exercise, gardening, and health talks. Researchers w…

This study is testing whether smelling lavender essential oil can help improve mental health and quality of life for women waiting to undergo IVF treatment. It will involve 120 women who are feeling anxious or stressed. Participants will be split into three groups: one will smell…

This study aims to find out which of three newer therapies works best to improve arm and hand function, reduce pain, and boost quality of life for people recovering from a stroke. Researchers will compare mirror therapy, a non-invasive brain stimulation technique, and robot-assis…

This study is testing whether a patient-controlled device that delivers gentle electrical stimulation to specific acupressure points can improve quality of life for people with chronic cancer pain. It will involve 290 adults with cancer who have ongoing pain. Researchers will mea…

This study aims to understand if surgically removing large, visible birthmarks (congenital melanocytic nevi) improves children's quality of life and reduces feelings of social stigma. Researchers will follow 100 children, aged 9 months to 16 years, comparing their experiences bef…

This study is testing whether a regular exercise program can improve reaction time and mouse-click accuracy for people who play video games. Researchers at the University of Miami are recruiting 15 student gamers to participate. The goal is to see if physical fitness can lead to …

This study is testing a redesigned ureteral stent to see if it causes fewer painful side effects than the standard version. It will involve 40 adults who have had surgery for kidney or ureteral stones. Researchers will compare the new and old stents by having patients complete qu…

This study compares two surgical techniques for low rectal cancer to see which one better preserves patients' bowel control and quality of life after surgery. Researchers will randomly assign 256 patients to receive either the Parks or Bacon surgical method and then track their b…

This study in Ukraine aims to find out which of two minimally invasive procedures works better for reducing severe nerve pain caused by combat injuries. Fifty adult patients with this type of pain will be randomly assigned to receive either a 'freezing' (cryoablation) or a 'heati…

This study is testing whether a combination of pain education and a tailored exercise program can help reduce pain, improve quality of life, and change negative thought patterns in women with endometriosis. Researchers at the University of Seville are enrolling 32 adult women dia…

This study is testing whether an 8-week virtual reality exercise program can help improve physical and mental health for women veterans. Researchers will compare 40 veterans who use the VR adventure games to a control group, measuring changes in activity levels, mood, stress, and…

This study is testing whether providing hearing aids can improve the quality of life for adult cancer patients. These patients have developed hearing loss or ringing in the ears (tinnitus) as a side effect of their platinum-based chemotherapy. Researchers will compare the well-be…

This study is testing whether a therapy called dry needling can help reduce pain and improve daily life for people with long-term low back pain. Researchers will compare three different dry needling session plans in 42 adults. The main goal is to see if the treatment plans are pr…

This study is testing whether CBD (cannabidiol) suppositories can help reduce pain during sexual activity and improve overall well-being. Researchers are enrolling 50 adults who experience sexual pain to try different doses of CBD suppositories for one month. The goal is to see i…

This study is testing whether weekly, supportive phone calls can improve mental health for homebound older adults. Over 8 weeks, trained volunteers will call 400 participants to provide social connection and support. Researchers want to see if these calls reduce feelings of lonel…

This study is testing whether a supervised aerobic exercise program, combined with education about pain, can help women with migraines. It will compare this approach to general recommendations for home-based physical activity. The goal is to see if exercise can reduce migraine-re…

This study is testing a 9-week program designed to improve the quality of life for older adults. It focuses on building personal strengths like resilience, gratitude, and acceptance to help manage stress and reduce feelings of loneliness, anxiety, and depression. The program invo…

This study is testing a new coaching program designed to help pregnant medical residents and fellows. The program aims to reduce burnout, improve well-being, and help them balance their demanding jobs with starting a family. About 48 participants will either receive the coaching …

This study is testing a free, 6-week online coaching program designed to help Nova Southeastern University undergraduate students manage anxiety, depression, and stress. About 160 students will be randomly assigned to either start the program immediately or be placed on a waitlis…

This study is testing whether taking a collagen supplement for 8 days can improve quality of life, appetite, and blood sugar levels in overweight adults. One hundred participants will take either the collagen supplement or a placebo, fill out questionnaires about their mood and e…

This research study aims to understand how stroke survivors' muscles respond when they imagine moving their arm or watch someone else move. Researchers will measure muscle activity in the wrist and fingers during these mental practice sessions to see how they relate to recovery. …

This study aims to understand how women's feelings about artificial intelligence relate to their anxiety levels and overall quality of life while they undergo infertility treatment. Researchers will survey 191 women aged 18-45 who are currently receiving fertility care. The goal …

This study aims to identify factors that predict how well older adults recover after surgery for gastrointestinal cancer. Researchers will follow 327 patients aged 65+ for up to 5 years after their curative-intent surgery at a hospital in Colombia. The goal is to understand what …

This study aims to understand the long-term health of children born to mothers who have had a solid organ transplant (like kidney, liver, or heart). Researchers want to see if these children have a higher risk of heart, kidney, or immune system problems later in life, possibly du…

This study aims to understand how a recurring pilonidal cyst affects a person's quality of life, pain, and daily activities. It will observe 100 patients whose cyst has returned after previous surgery or laser treatment. Researchers will collect information through questionnaires…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study is testing whether a digital dashboard tool helps community health workers deliver a family support program more effectively in Rwanda. The program, called Sugira Muryango, aims to improve caregiver mental health, reduce family violence, and support child development. …

This study aims to understand if a patient's mental health, like depression or anxiety, affects how severe their Graft-Versus-Host Disease (GvHD) symptoms are. Researchers will follow 200 adult patients with GvHD, using questionnaires to track their psychiatric status, physical s…

This study aims to understand how caring for a young child with a rare genetic disease affects a family's mental health and daily life. Researchers will survey 45 families in Turkey, measuring the child's ability to perform daily tasks and linking it to parents' stress, sleep, an…

This study aims to understand how sleep problems, specifically insomnia, develop in the first year after someone is diagnosed with cancer. Researchers will follow 260 patients who had no sleep issues at diagnosis, checking in regularly to track their sleep quality, pain, mood, an…

This study aims to understand what factors contribute to better quality of life for older adults living in nursing homes in Vietnam. Researchers will interview 176 residents in Hanoi to explore how things like health, independence, and social support affect their well-being. The …

This study aims to understand how common sleep problems affect memory, thinking skills, and overall well-being in people being treated for breast cancer. Researchers will observe 75 patients, using sleep trackers and questionnaires to measure sleep patterns and cognitive function…

This study aims to understand how breast cancer surgery affects patients' quality of life over five years. Researchers will follow 1,500 patients who undergo surgery, collecting detailed feedback through regular questionnaires. The goal is to gather real-world data to help improv…

This study aims to understand why some people develop long-term pain after surviving a serious illness in the Intensive Care Unit (ICU). Researchers will follow 800 Danish ICU survivors for up to a year, asking about their pain, sleep, mood, and quality of life. The goal is to id…

This study aims to understand how neuropathic (nerve) pain affects the ability to care for oneself and overall quality of life in people with Type 2 diabetes. Researchers will survey 128 adult volunteers with Type 2 diabetes, asking questions about their pain levels, daily activi…

This study aims to understand how a brief, full-body cold-water bath affects a person's choices, stress levels, and body signals. Forty healthy adults will take one cold bath and one warm bath about a month apart, while researchers measure their decisions in games, food preferenc…

This study aims to translate and test a questionnaire about involuntary movements (dyskinesia) in Parkinson's disease for Turkish-speaking patients. Researchers will enroll 130 people with Parkinson's to see if the translated questionnaire is reliable and accurately measures how …

This study aims to understand how painful nerve damage affects daily life and healthcare expenses for people with Sjögren's syndrome. Researchers will compare 100 patients with and without this nerve condition using questionnaires about pain, fatigue, and quality of life. The goa…

This study aims to find out if asking patients more often about their quality of life gives a better picture of the benefits of a heart procedure called catheter ablation. It will compare this procedure to standard medication in 70 adults who have a defibrillator and a dangerous …

This study follows women for 10 years after receiving Silimed brand smooth surface breast implants. Researchers want to understand both the expected and unexpected risks, as well as how satisfied women are with their results and quality of life. The goal is to gather long-term sa…