Could a simple alcohol injection ease endometrioma pain?

NCT ID NCT06955221

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 8 times

Summary

This study tests whether ultrasound-guided alcohol sclerotherapy can reduce pelvic pain and improve quality of life in women aged 18-45 with ovarian endometriomas. Participants are randomly assigned to receive the procedure or no treatment (expectant management) and are followed for 6 months. The goal is to see if this minimally invasive approach offers a better alternative to surgery or watchful waiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
alcohol sclerotherapy
What this could lead to
If it works, this could offer a less invasive option to manage endometrioma-related pain and improve quality of life without surgery.
What could go wrong
This is a mid-sized trial with no blinding, so results may be influenced by placebo effects. The procedure carries risks like infection or recurrence, and long-term benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clínica Sanabria

    NOT_YET_RECRUITING

    Granada, 18012, Spain

  • Consorci Corporació Sanitària Parc Taulí

    NOT_YET_RECRUITING

    Sabadell, Barcelona, 08208, Spain

  • Consorci Sanitari Integral

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08906, Spain

  • Consorci Sanitari de l'Anoia

    NOT_YET_RECRUITING

    Igualada, Barcelona, 08700, Spain

  • Hospital Clínico San Carlos

    RECRUITING

    Madrid, 28040, Spain

  • Hospital Clínico Universitario Lozano Blesa

    NOT_YET_RECRUITING

    Zaragoza, 50009, Spain

  • Hospital General Universitario Los Arcos del Mar Menor

    NOT_YET_RECRUITING

    San Javier, Murcia, 30739, Spain

  • Hospital General de Granollers

    NOT_YET_RECRUITING

    Granollers, Barcelona, 08042, Spain

  • Hospital Recoletas Salud Campo Grande

    RECRUITING

    Valladolid, 47007, Spain

  • Hospital San Juan de Dios de Martorell

    NOT_YET_RECRUITING

    Martorell, Barcelona, 08760, Spain

  • Hospital Universitari General de Catalunya

    NOT_YET_RECRUITING

    Sant Cugat del Vallès, Barcelona, 08195, Spain

  • Hospital Universitari Sant Joan de Reus

    NOT_YET_RECRUITING

    Reus, Tarragona, 43204, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Doctor José Molina Orosa

    NOT_YET_RECRUITING

    Arrecife, Canary Islands, 35500, Spain

  • Hospital Universitario Germans Trias i Pujol

    NOT_YET_RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Hospital Universitario Joan XXIII

    NOT_YET_RECRUITING

    Tarragona, 43005, Spain

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario San Pedro

    NOT_YET_RECRUITING

    Logroño, La Rioja, 26006, Spain

  • Hospital Universitario Son Espases

    NOT_YET_RECRUITING

    Palma de Mallorca, Balearic Islands, 07210, Spain

  • Hospital Universitario de Bellvitge

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Hospital Universitario de Burgos

    NOT_YET_RECRUITING

    Burgos, 09006, Spain

  • Hospital Universitario de Cabueñes

    NOT_YET_RECRUITING

    Gijón, Principality of Asturias, 33394, Spain

  • Hospital Universitario de Canarias

    NOT_YET_RECRUITING

    San Cristóbal de La Laguna, Santa Cruz De Tenerife, 38320, Spain

  • Hospital Universitario de Jaén

    NOT_YET_RECRUITING

    Jaén, 23007, Spain

  • Hospital Universitario de Álava - Txagorritxu

    NOT_YET_RECRUITING

    Vitoria-Gasteiz, Álava, 01009, Spain

  • Hospital de Viladecans

    RECRUITING

    Viladecans, Barcelona, 08840, Spain

  • Hospital del Mar

    RECRUITING

    Barcelona, 08003, Spain

  • Parc Sanitari Sant Joan de Deu

    NOT_YET_RECRUITING

    Sant Boi de Llobregat, Barcelona, 08830, Spain

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