Exercise may be a Drug-Free way to tame migraines

NCT ID NCT06716489

Recruiting now Symptom relief Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a supervised aerobic exercise program, combined with a single session of pain education, can reduce migraine-related disability and improve sensory and muscle function. One hundred women with migraine will either exercise on a treadmill three times a week for 16 weeks or receive standard physical activity advice. The goal is to find a safe, accessible, non-drug treatment for migraine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: supervised aerobic exercise plus pain neuroscience education
What this could lead to: If it works, this could offer a low-cost, non-drug option to help manage migraine symptoms and reduce headache-related disability.
What could go wrong: This is a small, early-stage trial with only 100 participants. The exercise program is time-intensive (3 times/week for 16 weeks), and results may not apply to all migraine sufferers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AEROBIC EXERCISE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

agnosia Headache headache disorder hypnic headache migraine disorder Motor Activity Neck Pain Sensation Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AEROBIC EXERCISE HEADACHE HEADACHE DISORDERS HEADACHE DISORDERS, PRIMARY HEADACHE, MIGRAINE MIGRAINE MIGRAINE DISEASE MIGRAINE DISORDER MIGRAINE DISORDERS, BRAIN PAIN MANAGEMENT PSYCHOSOCIAL FACTORS QUALITY OF LIFE SENSORY DISORDERS

Contacts and locations

Locations

Ribeirão Preto Medical School - University of São Paulo (FMRP-USP)
RECRUITING

Ribeirão Preto, São Paulo, 14049-900, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.