Exercise may be a Drug-Free way to tame migraines

NCT ID NCT06716489

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a supervised aerobic exercise program, combined with a single session of pain education, can reduce migraine-related disability and improve sensory and muscle function. One hundred women with migraine will either exercise on a treadmill three times a week for 16 weeks or receive standard physical activity advice. The goal is to find a safe, accessible, non-drug treatment for migraine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

supervised aerobic exercise plus pain neuroscience education

What this could lead to

If it works, this could offer a low-cost, non-drug option to help manage migraine symptoms and reduce headache-related disability.

What could go wrong

This is a small, early-stage trial with only 100 participants. The exercise program is time-intensive (3 times/week for 16 weeks), and results may not apply to all migraine sufferers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia Headache headache disorder hypnic headache migraine disorder Motor Activity Neck Pain Sensation Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ribeirão Preto Medical School - University of São Paulo (FMRP-USP)

    RECRUITING

    Ribeirão Preto, São Paulo, 14049-900, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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