University Of Sao Paulo

This study is testing a new smartphone tool called Tia Bete that uses artificial intelligence to help people with type 1 diabetes. The AI helps count carbohydrates in meals and suggests insulin doses in real-time. Researchers want to see if using this tool for six months improves…

This study compares two established bone graft surgeries for people who keep dislocating their shoulder. Sixty participants will be randomly assigned to receive either the Latarjet or the Modified Eden-Hybinette procedure. Researchers will track which surgery leads to better shou…

This study is testing a new one-day treatment for a common type of skin cancer called nodular basal cell carcinoma. Researchers are combining a standard light-based therapy with low-intensity ultrasound, hoping the sound waves help reach deeper cancer cells. The goal is to see if…

This study is testing whether using smartwatches and a special digital platform can help doctors monitor heart patients from home. It aims to see if this system can spot irregular heartbeats early and alert doctors quickly. The trial will involve 520 adults with heart conditions,…

This study is testing whether adding the medication lacosamide to standard treatments helps people with bipolar disorder who are experiencing a depressive episode that hasn't improved with other medications. Forty adults whose depression hasn't responded to at least two prior tre…

This study is testing whether a non-invasive device called REAC can help the brain recover after a severe traumatic injury. Researchers will enroll 60 patients with diffuse axonal injury (a type of brain damage) and randomly assign them to receive either the real REAC treatment o…

This study is testing whether a nutrition program can help lower the risk of heart disease in people with bipolar disorder. People with bipolar disorder have a much higher risk of heart problems. Researchers will work with 88 adults to see if following specific dietary guidelines…

This study is testing whether a single dose of ayahuasca (a traditional plant brew) or esketamine (a ketamine-based medicine) can help reduce symptoms of post-traumatic stress disorder (PTSD). It's a small, early-stage trial with 10 participants who have PTSD but no other major h…

This study is testing whether a single dose of ayahuasca (a traditional plant brew) or esketamine (a medication related to ketamine) can change how healthy women perceive their own bodies. Researchers will compare the two substances in a carefully controlled trial with 20 partici…

This study is testing if a special light therapy, used during dental cleaning, works better than standard cleaning alone to reduce bad breath in people who have both type 2 diabetes and serious gum disease. Researchers will compare the two treatments over six months to see which …

This study is testing a physical therapy program designed to help women recover from tears or cuts in the area between the vagina and anus that can happen during a first vaginal birth. Researchers want to see if adding pelvic floor muscle exercises and cold therapy to standard ca…

This study is testing whether a single dose of ayahuasca (a traditional psychedelic brew) or esketamine (a medication related to ketamine) can help reduce premenstrual symptoms like mood swings and physical discomfort. It will involve 20 healthy women who do not have other medica…

This study compares two methods for managing pain after minimally invasive surgery to correct pectus excavatum (a sunken chest). Researchers will test whether freezing the nerves between ribs (cryoanalgesia) works as well as or better than a traditional epidural pain block. The t…

This study is testing whether a gentle, non-invasive brain stimulation device can help people who have both anxiety and chronic insomnia. Thirty adults will receive 20 sessions of stimulation over four weeks to see if it reduces their anxiety and improves their sleep quality. The…

This study is testing whether a supervised aerobic exercise program, combined with education about pain, can help women with migraines. It will compare this approach to general recommendations for home-based physical activity. The goal is to see if exercise can reduce migraine-re…

This study is testing whether following specific dietary advice and taking probiotics can help reduce chronic pelvic pain in women who have both endometriosis and irritable bowel syndrome (IBS). Researchers will compare pain levels and quality of life in 74 participants who recei…