University Of Sao Paulo

This study tests a smartphone AI tool called Tia Bete that helps people with type 1 diabetes count carbohydrates and adjust their insulin doses in real time. Researchers will enroll 40 children and adults to use the tool for six months, measuring changes in blood sugar control an…

This study looks at whether starting strong anti-inflammatory drugs early can help control Vogt-Koyanagi-Harada (VKH) disease, a rare condition that causes eye inflammation and vision loss. About 40 people with newly diagnosed VKH will receive high-dose steroids and immune-suppre…

This study tests whether a natural compound called inorganic nitrate can help control high blood pressure in pregnant women with chronic hypertension. About 144 women will receive either nitrate or a placebo from the second trimester onward. The goal is to see if nitrate can safe…

This study tests whether a gel made from polynucleotides and hyaluronic acid, combined with a bone graft, can help repair deep gum and bone damage caused by periodontitis. About 66 adults with advanced gum disease will receive standard surgery alone, surgery with bone graft, or s…

This study compares two ways to manage pain after minimally invasive surgery for pectus excavatum (a sunken chest). One method freezes the nerves between the ribs (cryoanalgesia), and the other uses an epidural block. Researchers want to see which approach leads to a shorter hosp…

This study tests whether adding antimicrobial photodynamic therapy (aPDT) to standard gum cleaning and tongue scraping can better reduce bad breath in people with type 2 diabetes and advanced gum disease. About 32 adults will receive either standard care or standard care plus aPD…

This study tests a noninvasive device called REAC that uses gentle electrical signals to help rebalance brain activity in people with a severe type of traumatic brain injury called diffuse axonal injury (DAI). Researchers will compare real REAC treatment to a sham (fake) treatmen…

This study tests whether a single dose of ayahuasca or esketamine can ease symptoms of posttraumatic stress disorder (PTSD). Ten adults with PTSD will receive one of the two treatments in a double-blind, randomized setup. The goal is to see if either drug reduces PTSD symptoms qu…

This study looks at how a single dose of ayahuasca or esketamine changes the way healthy women see their bodies. Researchers will measure body image perception using a questionnaire. The goal is to understand if these substances can alter body perception in a positive way.