University Of Sao Paulo

This study tests whether taking high-dose omega-3 (fish oil) pills for 12 weeks can reduce inflammation and cell damage in women with lupus who have mild disease. Eighty women aged 18-45 will receive either omega-3 or a placebo. Researchers will measure changes in blood markers o…

This study tests a new type of testosterone implant made in Brazil for men with low testosterone (hypogonadism). Thirty men will receive four small implants under the skin that release testosterone over six months. The goal is to see if the implants safely raise testosterone leve…

This study compares a simpler, one-visit treatment called CTZ paste to the standard method for infected baby teeth in emergency dental settings. About 110 children will be randomly assigned to receive either CTZ paste or conventional treatment. The goal is to see if CTZ paste wor…

This study will test if a brief form of cognitive-behavioral therapy (CBT) can help prevent suicide in adults who have recently attempted suicide or had strong suicidal thoughts. About 150 people will be randomly assigned to either this brief CBT or standard supportive therapy fo…

This study tests whether empagliflozin, a medicine used for diabetes, can help reduce depression in people with bipolar disorder who also have insulin resistance. Insulin resistance is common in bipolar disorder and may make mood symptoms worse. The study will include 20 adults a…

This study compares two quick interventions—a single esketamine infusion or a one-session crisis planning talk—against standard care to prevent suicide in 468 people aged 14+ who recently attempted suicide or have severe suicidal thoughts. Participants will be followed for one ye…