Could exercise boost taurine in older women with obesity?

NCT ID NCT07711899

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Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jul 17, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This study investigates how taurine—a natural amino acid linked to inflammation and cell health—differs between metabolically healthy and unhealthy older women with obesity. Researchers will measure taurine levels before and after a 16-week combined exercise program. The goal is to understand whether exercise can influence taurine and potentially improve health in this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
16-week combined physical training program
What this could lead to
If successful, this could point toward low-cost exercise strategies to improve health in older women with obesity by understanding taurine's role.
What could go wrong
This is a small, early observational study with only 36 participants, so results may not apply broadly. It measures taurine levels, not clinical outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Mar 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 75 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Women aged 60 to 75 years. * Residents of the city or region of Ribeirão Preto, São Paulo, Brazil. * Physically inactive for at least 3 months. * Body mass index (BMI) ≥ 30 kg/m² (PAHO, 2002). * Body fat percentage ≥ 35%, according to obesity diagnostic criteria (Batsis et al., 2016; Rubino et al., 2025). Classified into one of two obesity phenotypes based on Zembic et al. (2021): Metabolically Healthy Obesity (MHO/OMS): all of the following criteria must be met: * Systolic blood pressure (SBP) \< 130 mmHg; * Waist-to-hip ratio \< 0.95; * Fasting blood glucose \< 126 mg/dL. Metabolically Unhealthy Obesity (MUO/OMNS): meets two or fewer of the above criteria. Exclusion Criteria Clinical conditions * Contraindication to physical exercise. * Current or previous diagnosis of: * Neoplasms; * Autoimmune diseases; * Hepatic diseases; * Coronary diseases; * Renal diseases; * Neurodegenerative diseases; * Infectious diseases. Previous or ongoing treatments * Use of medication for thyroid disorders. * Participation in exercise training programs, nutritional counseling, or weight loss treatment within the 3 months preceding the intervention. Lifestyle habits * Current smoking. * Alcohol consumption. For MHO Group: * Medication use * Hypoglycemic agents * Insulin (Bell, Kivimäki, \& Hamer, 2014). * Protocol adherence \*Attendance at less than 80% of the training sessions (De Carvalho et al., 2021).

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Obesity, Metabolically Benign

As listed by the trial registrant

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