Could a simple paste replace drilling for Kids' tooth infections?
NCT ID NCT07542639
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a new, simpler treatment called CTZ paste against the standard root canal procedure for infected baby teeth in emergency settings. The CTZ paste is placed directly into the tooth without drilling or cleaning the root canals, aiming to kill bacteria and save the tooth. Researchers will follow 110 children for one year to see if the paste controls pain and infection as well as the standard method, potentially making treatment faster and more accessible in public health clinics.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CTZ paste (chloramphenicol, tetracycline, zinc oxide, eugenol)
What this could lead to
If it works, this could offer a faster, simpler treatment option for infected baby teeth, making dental care more accessible in public health settings.
What could go wrong
This is a very early (Phase 1) trial with only 110 children at one center. The CTZ paste may not be as effective as the standard procedure, and long-term results are unknown.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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