University Of Sao Paulo
Clinical trials sponsored by University Of Sao Paulo, explained in plain language.
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Can common steroids heal COVID's lasting lung scars?
Disease control CompletedThis study tested whether a common steroid pill (prednisolone) could help people with lasting lung scarring and breathing problems after a severe COVID-19 infection. One hundred adults who still had abnormal lung scans and reduced lung function at least 12 weeks after their COVID…
Phase: PHASE1 • Sponsor: University of Sao Paulo • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Ancient brew vs modern drug: Head-to-Head depression battle
Disease control CompletedThis study tested whether four weekly doses of ayahuasca (a traditional plant brew) or esketamine (a modern antidepressant) could help people with severe depression. Researchers compared the two treatments in 22 carefully selected patients who had no other major health conditions…
Phase: PHASE2 • Sponsor: University of Sao Paulo • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Blue dye in blood wash may ease heart surgery recovery
Disease control CompletedThis study tested if adding a blue dye called methylene blue to a blood-cleaning process during heart surgery could help patients. The goal was to see if this method reduced harmful fluid buildup and body-wide inflammation after surgery. Researchers compared the new method agains…
Phase: PHASE2 • Sponsor: University of Sao Paulo • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Video calls for recovery: can remote therapy help stroke patients regain independence?
Symptom relief CompletedThis study tested whether occupational therapy delivered remotely through video calls could help stroke survivors improve their ability to perform daily activities like bathing, dressing, and cooking. Researchers compared a small group of patients who received this remote guidanc…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Can prayer ease migraine pain? study investigates
Symptom relief CompletedThis study tested whether praying could help people with migraines better tolerate pain and feel less anxious or depressed. It compared the effects of prayer to reading a neutral text in 100 participants, half with migraines and half without. Researchers measured pain thresholds …
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Zapping away depression? new brain treatment tested for seniors
Symptom relief CompletedThis study tested a non-drug treatment for depression in people over 60. Researchers used a magnetic device to gently stimulate specific areas of the brain, aiming to improve mood. They compared the real treatment to a fake (placebo) version in 108 participants to see if it safel…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Light and sound waves ease diabetic nerve pain
Symptom relief CompletedThis study tested whether a combination of laser light and ultrasound therapy could help people with early-stage diabetic nerve damage. Sixty participants received either the combined treatment or a placebo treatment twice a week. The results showed the treatment group had a sign…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 27, 2026 12:41 UTC
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Brain light therapy tested for Hard-to-Treat schizophrenia symptoms
Symptom relief CompletedThis study tested whether light therapy (photoneuromodulation) could help reduce the negative symptoms of schizophrenia in people who hadn't responded well to other treatments. Thirty participants received either real or fake light therapy sessions in a carefully controlled cross…
Phase: PHASE2 • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 25, 2026 14:09 UTC
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Could a psychiatric drug quiet ringing ears?
Symptom relief CompletedThis small, early-stage study tested whether olanzapine, a medication typically used for other conditions, could reduce the distress and perceived loudness of chronic tinnitus. Fifty adults with stable, long-term tinnitus tried the drug and a placebo in a random order. The main g…
Phase: PHASE1 • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Doctors uncover key clues to stop colon polyps from returning
Knowledge-focused CompletedThis study looked back at medical records to understand why some colon polyps grow back after being removed during a colonoscopy. Researchers analyzed data from 255 patients to identify which factors—like how the polyp was removed or its specific cell type—are most linked to recu…
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Heart Patients' activity levels mapped in new study
Knowledge-focused CompletedThis study aimed to understand how physically active people with heart rhythm problems (arrhythmias) are. Researchers surveyed 100 patients from a heart clinic to measure their activity levels and quality of life. The goal was to gather information that could help doctors better …
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC