University Of Sao Paulo

This study looked at whether adding probiotics or antibiotics to standard non-surgical gum disease treatment helps improve gum health. Sixty adults with severe periodontitis took part. The goal was to see if probiotics could be a safer alternative to antibiotics, which can cause …

This study looked at whether warming patients before digestive surgery helps keep their body temperature normal. 105 adults having cancer surgery were divided into three groups: one with standard blankets, and two using a forced-air warming system for 20 or 30 minutes. The study …

This study tested a porcine collagen matrix (Mucoderm) against the standard connective tissue graft for covering exposed tooth roots due to gum recession. Eighteen adults with gum recession on both sides of the mouth received one treatment on each side. The goal was to see if the…

This completed phase 1 trial tested whether the steroid prednisolone can help people with persistent lung damage after a moderate to severe COVID-19 infection. One hundred adults with abnormal lung scans and reduced lung function were randomly assigned to receive either prednisol…

This study tested a new method to reduce fluid buildup and inflammation in 124 adults having heart surgery with a heart-lung machine. The method involves washing the blood with methylene blue during a filtering process. Researchers measured fluid levels and inflammation markers b…

This study tested whether natural progesterone or a cervical pessary (a silicone ring placed in the vagina) is better at preventing early birth in pregnant women with a short cervix (25 mm or less). The trial included 203 women with a single baby. Researchers tracked how many gav…

This study tested whether taking probiotics (good bacteria) can reduce depressive symptoms in people with bipolar disorder. 141 adults were randomly assigned to receive either probiotics or a placebo for 12 weeks. The goal was to see if probiotics could improve mood and reduce de…

This study tested whether shining a red laser on the roof of the mouth after a gum graft procedure could reduce pain and help the area heal faster. Thirty adults who needed gum grafts took part. Half received laser treatment on the donor site, while the other half received standa…

This study looked at whether prayer can help people with migraines feel less pain and improve anxiety and depression. About 100 adults, half with migraines and half without, took part. They compared the effects of prayer versus reading a neutral text on pain sensitivity and emoti…

This study tested whether online occupational therapy sessions could help stroke survivors improve their ability to perform everyday tasks like bathing, dressing, and using the phone. Fifteen patients on a waiting list for rehab were randomly assigned to receive remote guidance o…

This study tested a combined laser and ultrasound treatment for people with type 2 diabetes who have early nerve damage in their feet. Sixty participants received either the real treatment or a placebo over 24 sessions. The results showed that the treatment helped reduce pain, bu…

This study tested whether four weekly doses of ayahuasca (a plant-based psychedelic drink) or esketamine (a nasal spray) could reduce symptoms in 22 adults with severe major depression. Participants were randomly assigned to one treatment, and their depression levels were tracked…

This study tested a non-invasive light therapy called photoneuromodulation in 30 adults with schizophrenia whose negative symptoms (like lack of motivation or social withdrawal) did not improve with standard treatments. Participants received either real or sham light sessions, th…

This study tested whether a gentle magnetic brain stimulation technique, called rTMS with theta-burst stimulation, can help treat depression in people over 60. Over 100 participants received either real or sham stimulation daily for about 4 weeks. The goal was to see if this non-…

This completed Phase 1 study tested whether olanzapine, an antipsychotic drug, can reduce the discomfort of tinnitus (ringing in the ears). Fifty adults with stable tinnitus for at least 6 months received either olanzapine or a placebo in a crossover design. The main goal was to …

This study looked at whether a remote physiotherapy session works as well as an in-person one for teaching pelvic floor exercises to women with urinary incontinence. 92 women who could not properly contract their pelvic floor muscles were randomly assigned to a face-to-face sessi…

This study from the University of Sao Paulo looked at whether measuring blood pressure during an exercise test can help predict outcomes in adults with flu-like symptoms, especially those who are unvaccinated. Researchers enrolled 62 participants and followed them for 30 days. Th…

This study looked at 90 people with low or medium heart risk to see if tiny, non-blocking plaques in the heart arteries affect how blood clots and how blood vessels work. Participants had a special CT scan to find these small plaques, and their blood was tested for clotting activ…

This study reviewed the medical records of 255 adults who had colorectal polyps removed during a colonoscopy. The goal was to find out which factors, such as how the polyp was removed or its tissue type, make it more likely to come back. Researchers also tracked any complications…

This completed study from the University of São Paulo measured physical activity levels and quality of life in 100 adults with cardiac arrhythmias. Researchers used questionnaires to see how active patients were and how they felt physically and mentally. The goal was to understan…