New gum fix: could a collagen patch replace the need for a second surgery?

NCT ID NCT03675334

Completed Disease control Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a porcine collagen matrix (Mucoderm) against the standard connective tissue graft for covering exposed tooth roots due to gum recession. Eighteen adults with gum recession on both sides of the mouth received one treatment on each side. The goal was to see if the collagen matrix could work as well as the graft, while avoiding the need for a second surgical site.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: porcine collagen matrix (Mucoderm)
What this could lead to: If successful, this could offer a simpler treatment for gum recession that avoids the need for a second surgical site to harvest tissue.
What could go wrong: This is a small, completed study with only 18 participants, so results may not apply to everyone. The collagen matrix may not work as well as the standard graft in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GINGIVAL RECESSION

Contacts and locations

Locations

School of Dentistry of Ribeirao Preto - University of Sao Paulo

Ribeirão Preto, São Paulo, Brazil

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