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Micro-needling vs. gum graft: a tiny trial tests a simpler fix for receding gums

NCT ID NCT05470660

Completed Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This pilot study tests whether micro-needling, combined with a gum-lifting procedure, can thicken receding gums as well as a standard gum graft substitute (Alloderm). Twenty-four adults with at least 3 mm of gum recession on a front tooth will receive one of the two treatments. The main goal is to see how much gum thickness increases after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a gum-lifting procedure (coronally advanced flap) combined with either micro-needling or a donated skin graft substitute (Alloderm)
What this could lead to
If micro-needling works as well as a graft substitute, it could offer a simpler, less invasive option for treating receding gums.
What could go wrong
This is a very small pilot study with only 24 people, so results may not apply widely. Micro-needling is a new approach for gum recession and may not thicken gums as effectively as the graft.

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Conditions

The condition(s) this trial relates to.

gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GINGIVAL RECESSION RECESSION, GINGIVAL THIN-GINGIVA

Contacts and locations

Locations

  • Faculty of Dentistry - Cairo University

    Cairo, Egypt

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Other studies related to the condition(s) this trial covers.