Can a numbing nose treatment stop migraine pain in its tracks?
NCT ID NCT07764783
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether applying a numbing medicine (lidocaine) to a nerve cluster inside the nose can quickly relieve migraine headaches, facial pain, and neck pain. Adults who have frequent headaches and facial pressure will receive either lidocaine or a saltwater placebo during a short scope-guided procedure. Researchers will track pain levels for 24 hours and monitor headache days over two months to see if the treatment helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A numbing medicine (lidocaine) applied directly to a nerve cluster inside the nose using a scope
- What this could lead to
- If it works, this could offer a quick, drug-free way to stop migraine pain and related facial or neck pain without needing daily pills.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to everyone. The procedure involves placing medicine in the nose, which could cause discomfort or side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ear, Nose, & Throat Surgeons of Western New England
Springfield, Massachusetts, 01107, United States
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