The eyes as a window to the brain: can a simple scan monitor MS, Alzheimer's, and Parkinson's?
NCT ID NCT07720765
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This study is testing whether a non-invasive eye scan called optical coherence tomography (OCT) can help track neurological diseases like multiple sclerosis, Alzheimer's, Parkinson's, and migraine. Over two years, researchers will measure the thickness of retinal layers in 840 patients and 210 healthy volunteers, comparing changes to standard clinical tests and brain imaging. The goal is to see if OCT can serve as a quick, painless way to monitor nerve damage in the brain over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Optical coherence tomography (OCT) — a non-invasive eye scan that measures retinal layer thickness
- What this could lead to
- If successful, this could establish OCT as a simple, routine tool to monitor nerve damage in common brain diseases, potentially catching changes earlier than current methods.
- What could go wrong
- This is an observational study, not a treatment trial. It will measure correlations, not prove that OCT improves patient outcomes. Results may not change practice if the scans don't reliably predict disease progression.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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IRCCS Ospedale San Raffaele - Neurology and Neurophysiology Unit
RECRUITINGMilan, Milano, 20132, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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