Irccs San Raffaele

This study is observing how well a special patch called PuraBond works to control bleeding during open surgery to repair the main artery in the abdomen (the aorta). It will include 100 adult patients in Italy who need this surgery for a bulging or blocked aorta. Doctors will appl…

This study is testing whether a safe, non-invasive electrical stimulation applied to the head and spine can make walking and balance training more effective for people with Parkinson's disease. 71 participants, including 51 with Parkinson's and 20 healthy volunteers, will undergo…

This study is testing if a single, high-precision dose of radiation is as effective and safe as the standard 5-dose treatment for certain early-stage breast cancers. It aims to see if the one-time treatment can control the cancer just as well while potentially being more convenie…

This study is testing a new combination of three drugs (Ibuprofen, G-CSF, and Plerixafor) to see if it safely and effectively collects stem cells from the blood of adults with X-linked Chronic Granulomatous Disease (X-CGD). The goal is to gather enough healthy stem cells so they …

This study aims to develop better ways to diagnose endometriosis and adenomyosis, two chronic conditions that affect women's reproductive health. Researchers will analyze blood samples, genetic information, and ultrasound images from 530 women, using artificial intelligence to fi…

This study aims to see if a faster, more widely available CT scan can be as good as the current standard MRI at spotting heart scarring and predicting future heart problems. It will enroll 2,200 adults who need a heart scan for reasons like chest pain or heart failure. The main g…

This study aims to find better ways to tell which pancreatic cysts are harmless and which might turn into cancer. Researchers will analyze samples from 800 people with these cysts, looking for patterns in their genes, environment, and body chemistry. The goal is to create a new t…

This study is testing a new digital platform designed to detect very early signs of Alzheimer's disease. Researchers will use non-invasive tools like brain wave monitors and eye-tracking devices on 100 participants, some with mild memory concerns and some healthy, over 12 months.…

This study is testing a simple blood test that measures a protein called S100B to help doctors quickly assess patients who come to the emergency room with a head injury. The goal is to see if the test can accurately identify patients who do NOT have a serious brain injury, which …

This study is testing whether a special type of MRI scan can accurately predict how aggressive a small kidney tumor is before a patient has surgery. Researchers will compare the MRI results with detailed analysis of the tumor tissue removed during the operation. The goal is to he…

This study is testing a new type of CT scanner to see if it can find liver cancer that has spread from colorectal cancer as well as or better than an MRI scan. It will involve 100 adults with colorectal cancer who will get both scans. The goal is to see if this new scanner, which…

This study is testing a new type of CT scan that can look at both the lungs and heart at the same time in people with interstitial lung disease (ILD). The goal is to find early signs of heart problems, which are common and serious in ILD but often missed until it's too late. Rese…

This study is testing a home-based virtual reality (VR) therapy program designed to improve hand and arm function in people with multiple sclerosis (MS). Sixty participants will use VR headsets at home for 15 sessions over three weeks, with one group watching and practicing hand …

This study is testing whether adding virtual reality (VR) to standard neck exercises helps people with chronic neck pain or whiplash feel better. 72 participants will do rehab exercises twice a week for six weeks, with half using a VR headset and half doing the same exercises wit…

This study aims to understand how pancreatic cancer changes at a molecular level during standard chemotherapy treatment. Researchers will collect small tumor samples from 80 patients with non-metastatic pancreatic cancer before and after they receive chemotherapy. By analyzing th…

This study is creating a large European database to track how people with serious deep vein problems in their legs are treated and how they do over 10 years. It will follow 100 patients who have newly diagnosed deep vein disease to collect real-world information on different trea…

This study aims to build a large database of detailed medical images and health information from 50,000 adults. Researchers will collect data from advanced CT and MRI scans, along with lab results and health records, to look for hidden patterns in the images. The goal is to disco…

This study aims to find better ways to detect bowel scarring (fibrosis) in people with ulcerative colitis. Researchers will test if special ultrasound scans can accurately measure this scarring by comparing scan results to actual tissue samples taken during routine colonoscopies.…

This study aims to understand how different first-line chemo-immunotherapy treatments for advanced lung cancer affect patients' quality of life, symptoms, and emotional health. Researchers will ask 144 patients to complete regular online questionnaires about their well-being, sle…

This study aims to understand the connections between bone health, muscle, and the body's energy use by analyzing existing hospital records. Researchers will look at past blood and urine test results from up to 1,000 adults to see how different biomarkers relate to each other bas…

This study aims to learn which of three standard procedures works best for treating stomach blockages caused by pancreatic cancer. Researchers will observe 250 patients who receive either surgery, an internal metal stent, or a newer endoscopic bypass procedure. They will compare …

This study aims to understand why some patients with neuroendocrine tumors respond better to treatments than others. Researchers will analyze medical records from 450 patients who received standard treatments to identify factors that influence how long treatments keep the cancer …