Irccs San Raffaele

This study tested a drug called sacituzumab govitecan given before bladder removal surgery in 44 people with muscle-invasive bladder cancer who could not take or refused standard cisplatin chemotherapy. The goal was to see if the drug could completely eliminate the tumor by the t…

This study tested an AI software called Quantib Prostate to see if it can detect prostate cancer on MRI scans as accurately as expert radiologists. Researchers looked at 200 men who had prostate MRIs and biopsies. The AI's readings were compared to the radiologist's readings, usi…

This study looked at tiny particles called extracellular vesicles (EVs) found in prostate fluid from 100 men. The goal was to find unique molecular signatures that could help tell aggressive prostate cancer from slow-growing or benign conditions. Researchers used advanced techniq…

This study looked at 30 men with prostate cancer to understand why MRI and PSMA-PET scans sometimes spot different tumors. Researchers used stored tissue samples to analyze the genes and molecules of these mismatched lesions. The goal was to find out if these differences mean the…

This study looked at 185 men with low-risk prostate cancer who chose active surveillance (monitoring instead of immediate treatment). Researchers used a genetic test called a polygenic risk score to see if it could predict which men would have their cancer get worse over time. Th…

This study tested whether it is safe and possible to collect a blood sample from the portal vein (a major liver blood vessel) during a routine endoscopic ultrasound in 23 people with pancreatic cancer. The goal was to find and count circulating tumor cells (cancer cells in the bl…

This study reviewed medical records of 200 adults from an endocrinology clinic to see if taking vitamin D3 supplements lowered their chances of developing Long COVID after a COVID-19 infection or getting COVID-19 after vaccination. Researchers compared patients who took vitamin D…

This completed study looked at 100,000 patient records to find out if people with eosinophilic esophagitis (EoE) are more likely to develop esophageal cancer. The researchers wanted to see if any increased risk is due to EoE itself or to other conditions like acid reflux or Barre…

This completed study tested whether artificial intelligence could analyze CT scans of the heart to better predict who is at risk for heart attacks or death. Researchers looked at data from 2190 patients with coronary artery disease. The goal was to create a risk score that goes b…

This study looked at 4,000 adults who had a heart MRI to find out how often a small heart valve variation called mitral annular disjunction (MAD) occurs. Researchers wanted to see if MAD is linked to heart valve problems or dangerous heart rhythms. The goal was to better understa…

This study looked at whether artificial intelligence (AI) can help predict the risk of heart attacks in people with early signs of heart disease. Researchers analyzed heart scans and health data from 3000 patients. The goal was to find a better way to identify who needs more aggr…

This study tested two different ways to remove leftover glue from teeth after braces are taken off. 142 people who had braces or clear aligners were split into two groups: one used a special ultrasonic tool, the other used a polishing bur. Researchers checked plaque, bleeding, le…

This completed study tested whether a one-and-a-half-hour lecture on moral reasoning could improve how people justify moral decisions. 86 healthy university students were split into two groups: one received the moral reasoning lecture, the other a lecture on logical reasoning. Re…

This study tested 40 healthy adults—20 smokers and 20 non-smokers—to see how smoking one cigarette changes blood vessels in the eye. Using special cameras, researchers measured blood vessel size and function before and after smoking. The goal was to understand the immediate effec…

This study looked at 159 people with ulcerative colitis who started a new advanced therapy. Researchers examined tissue samples from the colon to see if microscopic signs of inflammation could predict future problems like hospital stays or surgery. The goal is to help doctors dec…