Irccs San Raffaele
Clinical trials sponsored by Irccs San Raffaele, explained in plain language.
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Gentle Clean-Up: new tools battle braces glue without harming teeth
Disease control CompletedThis study compared two newer, gentler methods for cleaning leftover glue off teeth after braces are removed. Researchers tested 142 patients to see which method—a two-step ultrasonic tool or a one-step polishing bur—was better at removing the glue while causing less damage to th…
Sponsor: IRCCS San Raffaele • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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AI heart scan could spot hidden heart attack danger
Diagnosis CompletedThis study tested whether artificial intelligence (AI) could analyze standard heart CT scans to better predict which patients with coronary artery disease are at high risk for future heart attacks or other major heart problems. Researchers applied AI to scan images from over 2,00…
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated Mar 27, 2026 12:39 UTC
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Smoking's immediate impact on eye health revealed in new study
Knowledge-focused CompletedThis study looked at how smoking affects the tiny blood vessels in the back of the eye. Researchers compared 20 young adult smokers to 20 non-smokers using special eye scans. They measured changes in blood vessel size and function right after smoking to understand smoking's immed…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Genetic crystal ball for prostate cancer?
Knowledge-focused CompletedThis study looked at whether a genetic test, called a polygenic risk score, can predict if early-stage prostate cancer will get worse in men who are being monitored instead of immediately treated. Researchers analyzed DNA from 185 men with low-risk prostate cancer who were on act…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Can a single class change how you think about right and wrong?
Knowledge-focused CompletedThis study tested whether a single seminar on moral reasoning could improve how people explain their decisions in tricky moral situations. Researchers worked with 86 university students, comparing a moral reasoning seminar to a non-moral one. They measured how well participants c…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists test new way to spy on pancreatic cancer cells
Knowledge-focused CompletedThis study tested a new method to collect and analyze cancer cells from the blood of pancreatic cancer patients. During a standard diagnostic procedure, doctors took an extra blood sample from a specific vein near the liver to see if the cancer cells found there could help predic…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists hunt for cancer clues in urine
Knowledge-focused CompletedThis study aimed to learn more about prostate cancer by analyzing tiny particles called extracellular vesicles found in a specific type of urine sample. Researchers looked at samples from 100 men who had already been diagnosed, comparing those with more serious cancer to those wi…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC
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Massive data dive: does this chronic throat condition lead to cancer?
Knowledge-focused CompletedThis study aimed to find out if people with eosinophilic esophagitis (EoE), a chronic inflammatory throat condition, have a higher risk of developing esophageal cancer. Researchers analyzed the medical records of 100,000 patients to see if the cancer risk comes from EoE itself or…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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Heart scans uncover mystery of valve flaw linked to sudden death
Knowledge-focused CompletedThis study looked back at heart MRI scans from 4,000 people to understand a feature called mitral annular disjunction (MAD). Researchers wanted to see how common MAD is and if it is linked to a floppy heart valve or dangerous irregular heartbeats. The goal is to gather knowledge …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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When scans disagree: scientists probe hidden prostate cancer clues
Knowledge-focused CompletedThis study aimed to understand why two advanced scans for prostate cancer sometimes detect different areas of concern. Researchers analyzed stored tissue samples from 30 patients to see what makes these 'discordant' lesions different at a molecular level. The goal was to help doc…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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AI steps in to predict your heart attack risk
Knowledge-focused CompletedThis study aims to develop an artificial intelligence (AI) tool to better predict which patients with early signs of heart disease are at highest risk of having a heart attack or dying from heart problems. Researchers will analyze CT scans and health data from 3,000 patients to t…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:55 UTC
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Hidden gut damage could predict future flares in colitis patients
Knowledge-focused CompletedThis study looked back at the medical records of 159 people with ulcerative colitis (UC) who were on newer, advanced medications. Researchers wanted to see if finding microscopic inflammation in colon tissue biopsies, even when the colon looks mostly okay during a scope exam, cou…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:23 UTC