Irccs San Raffaele
Clinical trials sponsored by Irccs San Raffaele, explained in plain language.
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New drug shows promise for tough bladder cancer cases
Disease control CompletedThis study tested a drug called sacituzumab govitecan in 44 people with muscle-invasive bladder cancer who could not take or refused standard cisplatin chemotherapy. The drug was given before surgery to remove the bladder, aiming to wipe out all cancer cells. The main goal was to…
Phase: PHASE2 • Sponsor: IRCCS San Raffaele • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Prostate cancer clues found in urine particles
Diagnosis CompletedThis study looked at tiny particles called extracellular vesicles (EVs) found in urine after a prostate exam. Researchers analyzed these particles from 100 men to find patterns that could help tell aggressive prostate cancer from less serious cases. The goal is to develop a new, …
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated May 06, 2026 16:14 UTC
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Hidden clues in biopsies may predict UC trouble ahead
Knowledge-focused CompletedThis study looked at 159 people with ulcerative colitis who started a new advanced treatment. Researchers wanted to see if tiny signs of inflammation found in biopsies (called histologic activity) could predict future problems like hospital stays or surgery, even when the colon l…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:51 UTC
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Vitamin D3 may lower long COVID risk, new study suggests
Knowledge-focused CompletedThis study reviewed medical records of 200 adults from an endocrinology clinic to see if taking vitamin D3 supplements lowered their chances of developing Long COVID after a COVID-19 infection or getting COVID-19 after vaccination. Researchers compared patients who took vitamin D…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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New blood draw from Liver's vein could reveal pancreatic cancer secrets
Knowledge-focused CompletedThis study tested if it is safe and possible to collect a blood sample from the portal vein (a major vein near the liver) during a routine endoscopic ultrasound in 23 people with pancreatic cancer. The goal was to find and count circulating tumor cells (cancer cells that have bro…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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Smoking changes eye blood vessels, study finds
Knowledge-focused CompletedThis study looked at how smoking affects the blood vessels in the back of the eye. Researchers compared 20 healthy smokers with 20 non-smokers, using special eye scans to measure vessel size and response to light. The goal was to understand the immediate effects of smoking on eye…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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Massive study probes cancer risk in eosinophilic esophagitis patients
Knowledge-focused CompletedThis study looked at health records from about 100 million people to find out if those with eosinophilic esophagitis (EoE) are more likely to develop esophageal cancer. The researchers wanted to see if any increased risk is due to EoE itself or to other common conditions like GER…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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AI could predict heart attacks before they happen
Knowledge-focused CompletedThis study looked at 3000 patients with suspected coronary artery disease to see if artificial intelligence could better predict who is at risk for a heart attack or death. Researchers used heart scan images and patient data to create a risk score. The goal is to help doctors dec…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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Brain training for better moral choices? study tests reasoning exercise
Knowledge-focused CompletedThis study looked at whether a short moral reasoning exercise could improve how people explain their moral choices. 86 healthy university students took part. The researchers compared the effects of a moral reasoning exercise to a non-moral one, measuring changes in the quality of…
Phase: NA • Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Prostate cancer mystery: why do two top scans disagree?
Knowledge-focused CompletedThis study looked at 30 men with prostate cancer to understand why MRI and PSMA-PET scans sometimes find different cancer spots. Researchers used stored tissue samples to study the genes and molecules of these mismatched spots. The goal was to learn if these spots are harmless, a…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 13, 2026 16:04 UTC
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Gene score may predict prostate cancer worsening
Knowledge-focused CompletedThis study looked at 185 men with low-risk prostate cancer who chose active surveillance (monitoring instead of immediate treatment). Researchers used a genetic risk score based on common DNA variants to see if it could predict when the cancer might progress. The goal is to help …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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AI reads heart scans to spot hidden danger
Knowledge-focused CompletedThis study looked at CT scans from 2190 people with coronary artery disease to see if artificial intelligence (AI) could help predict who is at higher risk for heart attacks or other serious heart problems. The researchers used AI to measure subtle features around the heart's art…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC
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Braces removal: which Clean-Up method is kinder to your teeth?
Knowledge-focused CompletedThis study looked at 142 people who had braces or clear aligners removed. It compared two gentle cleaning methods to remove leftover glue from teeth: one using a special ultrasonic tool and another using a polishing bur. The goal was to see which method causes less damage to the …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Heart MRI study reveals hidden valve variation in thousands
Knowledge-focused CompletedThis study looked at 4,000 adults who had a heart MRI to find out how often a condition called Mitral Annular Disjunction (MAD) occurs. MAD is a slight shift in where the heart valve attaches, and it may be linked to heart rhythm problems. The goal was to measure how common MAD i…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 12, 2026 13:44 UTC