New drug shows promise for Tough-to-Treat bladder cancer before surgery

NCT ID NCT05226117

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called sacituzumab govitecan given before bladder removal surgery in 44 people with muscle-invasive bladder cancer who could not take or refused standard cisplatin chemotherapy. The goal was to see if the drug could completely eliminate the tumor by the time of surgery. The study also looked at how well the drug shrank tumors on scans and how safe it was.

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Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy