Irccs San Raffaele

This study reviews medical records of 36 adults with relapsed or refractory PCNSL, a rare and aggressive brain lymphoma. Researchers want to see how well ibrutinib works alone or combined with R-CHOP chemotherapy. The goal is to measure tumor shrinkage and survival, while checkin…

This study looks at whether people with HIV can get their long-acting injections at home instead of at the hospital. About 120 adults who are already stable on HIV medication will be randomly assigned to receive injections either at home or in the hospital. The goal is to see whi…

This study looks at whether a special type of scan (PET/MRI) can predict how well esophageal cancer responds to chemotherapy and radiation given before surgery. About 121 adults with esophageal or stomach-junction cancer will be scanned before, during, and after treatment. The go…

This study examines 100 people with a certain type of advanced lung cancer (EGFR-mutated NSCLC) to see how often they have a DNA repair problem called HRD. Researchers will look at tumor samples and medical records to find links between HRD and how the cancer behaves. The goal is…

This study looks at whether virtual reality training before Gamma Knife brain surgery can improve pain relief for people with trigeminal neuralgia, a severe facial pain condition. Researchers will also use MRI scans and artificial intelligence to find brain patterns that predict …

This study aims to understand how kidney tumors in people with von Hippel-Lindau (VHL) syndrome differ from one another and within the same tumor. Researchers will use advanced imaging, multiple biopsies, and lab-grown tumor models to map these differences. The goal is to gather …

This study looks at how diseases like frontotemporal dementia and ALS spread through the brain's network, called the connectome. Researchers will use MRI scans and other tests to track changes over two years in 645 people, including patients and healthy volunteers. The goal is to…

This study looks at data from 5,000 people who had IVF between 2019 and 2024. Researchers will use machine learning to find patterns that predict whether a pregnancy is likely to succeed. The goal is to help doctors personalize treatment—like choosing the best embryo or timing—to…

This study looks at two new, faster methods for thawing frozen eggs and compares them to the standard technique. Researchers will check how many eggs survive and how healthy they look after thawing. The study uses eggs donated for research from 399 women aged 20-39. It aims to fi…

This study aims to create a questionnaire that measures how patients feel during an endoscopic ultrasound, a procedure used to examine the pancreas and bile ducts. Researchers will ask 171 outpatients at an Italian hospital about their experience and compare their answers with th…

This study is a registry that collects information from 200 adults with a type of aortic dissection (a tear in the main artery) treated with a specific procedure called STABILISE. The goal is to see how well the procedure works and what complications may occur. No new treatment i…

This study is creating a large collection of biological samples and health data from 3,000 people. The goal is to help researchers better understand gynecological disorders, male and female infertility, and pregnancy-related conditions. Participants provide samples and informatio…