New scan could predict who benefits from esophageal cancer therapy

NCT ID NCT04359732

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether a special PET/MRI scan can predict how well esophageal cancer responds to chemotherapy and radiation given before surgery. Researchers will scan 121 patients during treatment and compare the images with the actual tumor response seen after surgery. The goal is to find imaging markers that identify responders early, potentially guiding more personalized care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hybrid PET/MRI scan

What this could lead to

If successful, this could help doctors personalize treatment by identifying which patients respond well to chemo-radiation before surgery.

What could go wrong

This is an observational imaging study, not a treatment trial. It may not change outcomes directly, and results may not apply to all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms gastroesophageal junction adenocarcinoma neoplasm of esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Deaprtment of Radiology, IRCCS Ospedale San Raffaele

    Milan, 20132, Italy