Can surgery for stomach or esophageal cancer cloud the mind?

NCT ID NCT06687291

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study follows 130 adults undergoing surgery for stomach or esophageal cancer to see how often they experience postoperative delirium—a state of confusion and disorientation after anesthesia. Researchers will also check whether depression, frailty, poor nutrition, or muscle loss before surgery make delirium more likely. Participants who experience delirium may be invited to share their experience in an interview, helping doctors understand and potentially prevent this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could identify risk factors for postoperative delirium and guide better supportive care for gastroesophageal cancer patients.
What could go wrong
As an observational study, it cannot prove cause and effect. Results may be limited by the specific patient group and may not apply to all cancer surgeries.

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Conditions

The condition(s) this trial relates to.

Chemotherapy-Related Cognitive Impairment Depression depressive disorder Emergence Delirium esophageal cancer Frailty gastric cancer gastroesophageal cancer Malnutrition nutritional deficiency disease Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karolinska University Hospital, Huddinge

    RECRUITING

    Huddinge, 14157, Sweden

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