CHEMOTHERAPY

This study looks at 340 people with high-risk stage II colorectal cancer who still have tumor DNA in their blood one month after surgery. Researchers want to see if using this blood test to decide on stronger chemotherapy can help clear the cancer DNA and improve survival. The go…

This study looks at whether radiation therapy to the underarm area is as effective as surgery to remove lymph nodes in breast cancer patients who still have cancer in their sentinel node after chemotherapy. The goal is to see if radiation causes less arm swelling (lymphedema) whi…

This study is for people with advanced non-small cell lung cancer (stage IIIB/C-IV) who cannot tolerate standard chemoradiation. It tests a sequence of platinum-based chemotherapy, followed by a special type of radiation (hypofractionated radiotherapy), and then the immunotherapy…

This study tests whether a combination of chemotherapy and radiation before surgery (total neoadjuvant therapy) can help about half of rectal cancer patients achieve a complete response, allowing them to avoid surgery and preserve their rectum through a watch-and-wait strategy. T…

This study tests whether a blood test that detects tumor DNA can help doctors decide how long chemotherapy should last for people with certain types of colorectal cancer. About 340 adults with T4N0 or low-risk stage III colorectal cancer will be randomly assigned to standard 3-mo…

This study tests whether adding low-dose radiation and an immunotherapy drug (cadonilimab) to standard chemotherapy can help people with advanced nasopharyngeal cancer live longer without the cancer coming back. About 380 adults aged 18-70 with newly diagnosed, advanced-stage dis…

This study tests whether adding a natural supplement (β-hydroxybutyrate) to a standard treatment plan can help shrink or eliminate rectal cancer before surgery. The plan includes short-course radiation, immunotherapy, and chemotherapy. The goal is to see if more patients achieve …

This study is for people with advanced stomach cancer that has spread and who have already tried one type of treatment. It tests a combination of three drugs (ramucirumab, nal-IRI, and trifluridine/tipiracil) to see if they can shrink tumors and control the disease. The goal is t…

This study is for people with high-risk stage III colorectal cancer. It uses a blood test (ctDNA) to see if adding a targeted drug (bevacizumab) to standard chemotherapy works better than chemo alone. About 100 participants will be randomly assigned to one of two treatment groups…

This study is for people with advanced gastroesophageal junction cancer that cannot be removed with surgery. It tests a combination of targeted radiation, immunotherapy, and chemotherapy to shrink the tumor enough so that surgery becomes possible. About 88 adults will take part t…

This study looks at whether painting mandalas during chemotherapy can help reduce anxiety, nausea, and improve comfort. Researchers will ask 120 first-time chemotherapy patients to color mandalas for at least 30 minutes during their treatment. Their anxiety, nausea, and comfort l…

This study tests whether a traditional Chinese medicine technique called acupoint application can help relieve constipation and qi deficiency in people with colorectal cancer who have had chemotherapy. About 106 adults will be randomly assigned to receive either the acupoint trea…

This study tests a nurse-led program to help cancer patients be more physically active while receiving treatment in an outpatient clinic. The goal is to see if the program is practical and can improve patients' well-being and mood. About 50 adults with cancer will take part, and …

This study compares two relaxing activities—art therapy and mandala drawing—to see which one better reduces anxiety in people receiving chemotherapy. Sixty adults currently on chemo will be randomly assigned to one of the two groups. Their anxiety levels will be measured before a…

This study tests if a special type of acupuncture (on the tongue area) can help cancer patients who have a bad or lost sense of taste from chemotherapy. 75 patients will either get real acupuncture, fake acupuncture, or standard dietary advice. The goal is to see if acupuncture c…

This study tests whether combining electroacupuncture (a gentle electric current through thin needles) with self-acupressure (pressing specific points on the body) can improve quality of life for people with early-stage breast cancer who are undergoing chemotherapy. About 192 par…

This study tests whether a mobile app that tracks symptoms and sensor data can help people receiving chemotherapy feel better and stay connected with their care team. About 50 adults with solid tumors will use the app and a Fitbit for 90 days. The goal is to see if the app is eas…

This study tests a program called MAEva, which combines meditation and acceptance techniques, to see if it helps improve quality of life for people treated for non-metastatic breast cancer. About 190 participants will be randomly assigned to either the MAEva program or a discussi…

This study aims to find early signs in the brain that can predict if a glioblastoma patient will survive at least 6 months after starting bevacizumab. Researchers will use special MRI scans to measure certain chemicals in the tumor. The goal is to help doctors decide which patien…

This study looks at adults aged 65 and older who are starting chemotherapy. Researchers will measure their resilience and create personalized care plans to better support them. The goal is to learn what these patients need and improve their experience during treatment.

This study tests a method called bioelectrical impedance to monitor fluid retention (edema) in cancer patients. It includes 46 people: breast cancer patients with arm swelling after radiotherapy and hospitalized patients with leg swelling after chemotherapy. Participants will hav…

This study looks back at medical records of 350 people with cervical cancer that has come back or spread to only a few places. The goal is to see how well different treatments like radiation, surgery, or chemotherapy work. By understanding what helps these patients live longer, d…

This study explores whether cancer patients undergoing chemotherapy can monitor their own blood counts at home instead of traveling to the hospital for every test. About 265 adults with cancer from Denmark, Poland, and Germany will participate, with some using home monitoring and…