Radiation to the gut boosts cancer-killing power of immunotherapy in esophageal cancer trial

This study tests whether adding a single, low dose of radiation to the small intestine can make a standard immunotherapy-plus-chemotherapy regimen work better for people with esophageal cancer that cannot be easily removed by surgery. About 43 adults with borderline resectable or unresectable esophageal squamous cell carcinoma will receive the combination treatment for three cycles, then be evaluated for surgery. The main goal is to see how many patients have no cancer cells left in their surgical tissue sample.