Radiation to the gut boosts cancer-killing power of immunotherapy in esophageal cancer trial

NCT ID NCT07339488

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a single, low dose of radiation to the small intestine can make a standard immunotherapy-plus-chemotherapy regimen work better for people with esophageal cancer that cannot be easily removed by surgery. About 43 adults with borderline resectable or unresectable esophageal squamous cell carcinoma will receive the combination treatment for three cycles, then be evaluated for surgery. The main goal is to see how many patients have no cancer cells left in their surgical tissue sample.

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Conditions

The condition(s) this trial relates to.

esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital, Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, 515031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••