Shielding the ovaries: a drug may help young breast cancer patients preserve fertility during chemo
NCT ID NCT07127315
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial tests whether giving goserelin, a hormone-blocking drug, alongside chemotherapy can help preserve ovarian function and fertility in premenopausal women with breast cancer. Participants receive either chemotherapy plus goserelin or chemotherapy alone. Researchers will measure hormone levels and long-term outcomes like disease-free and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Goserelin, a gonadotropin-releasing hormone agonist, given alongside chemotherapy
- What this could lead to
- If effective, this approach could help preserve fertility and ovarian function in young breast cancer patients undergoing chemotherapy.
- What could go wrong
- The trial is relatively small and early, and results may not apply to all patients. Goserelin has side effects and may not fully protect ovarian function.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Helwan University
Helwan, Helwan, 11795, Egypt
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