MALNUTRITION

This pilot study tests whether giving special nutritional shakes before and after surgery can improve the health of patients with critical limb ischemia, a severe form of peripheral artery disease. About 30 participants will drink the shakes for one to two weeks before and after …

This study looks at whether giving patients with bone or soft tissue sarcoma a special nutritional supplement twice daily before surgery can reduce complications and help maintain muscle mass. About 100 adults scheduled for tumor removal will be randomly assigned to receive eithe…

This study looks at whether eating protein evenly throughout the day, combined with a regular exercise program, can improve nutrition, muscle mass, and strength in people with end-stage liver disease awaiting a transplant. 90 participants will be split into three groups: one with…

This study tests whether early, personalized nutritional support and a simple home exercise program can prevent weight loss and improve quality of life in 200 adults with lung, colorectal, ovarian, or pancreatic cancer starting palliative chemotherapy. Participants receive guidan…

This study tests a new, personalized version of a weight-loss surgery called SADI-S. Surgeons will measure each patient's small intestine and adjust the bypass length to maximize weight loss while lowering the risk of vitamin deficiencies. The study includes 40 adults with obesit…

This study looks at how safe SMOFlipid is for children and adults who need IV nutrition for 8 weeks or more. It checks if the treatment causes a lack of essential fats or liver problems. About 100 participants will be followed to see how their bodies respond.

This study tests whether giving older patients at risk of malnutrition a food package, protein drinks, and dietitian support after hospital discharge can reduce readmissions and improve health. Researchers will enroll 2,000 patients aged 50 and older who are discharged with a lia…

This study tests whether a supervised exercise program combined with oral nutritional supplements can prevent disability in hospitalized adults aged 75 and older who are malnourished or at risk. Around 102 participants will be randomly assigned to either the exercise-plus-nutriti…

This study is testing the safety of Omegaven, a fish oil-based fat emulsion, in 40 children under 18 who have developed liver problems (cholestasis) from long-term IV nutrition. The main goal is to see how many children develop essential fatty acid deficiency during at least 8 we…

This study tests whether remote nutritional counseling helps cancer patients stick to their treatment plan and feel better. 240 adults with invasive cancer starting therapy will receive either a single consultation with written materials or a more intensive program with monthly f…

This study tests whether a low dose of pancreatic enzymes (pancrelipase) taken with a nutritional supplement can help older adults at risk of malnutrition absorb nutrients better. Twenty hospitalized patients aged 70 or older will receive either the enzymes or a placebo alongside…

This study investigates whether older adults with age-related hearing loss (presbycusis) can still hear and enjoy the sound of a crunchy biscuit while eating. Researchers will compare a crunchy biscuit with a soft one in 100 seniors aged 65 and older, asking them if they hear the…

This study is testing whether giving elderly patients with a broken hip and high frailty a special nutritional drink before surgery can help them stay more stable during the operation and recover better. Researchers will compare patients who get the drink with those who follow st…

This study looks at how common muscle loss and weakness are in people with liver cirrhosis, and how malnutrition plays a role. Researchers will use ultrasound to measure muscle size and a grip test to check strength. The goal is to better understand the problem and its impact on …

This study looks at how nutrition and body composition (like muscle and fat) impact the health of people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 300 participants starting new medical treatments or having sur…

This study tracks 300 adults who developed a surgical site infection after orthopedic surgery on their limbs or spine. Researchers will use questionnaires to measure how often depression and malnutrition occur over one year. The goal is to better understand these complications so…

This observational study follows 334 adults with type 2 diabetes or drug-induced diabetes who are malnourished or at risk. Researchers will track their nutritional treatment patterns after being prescribed a special high-calorie, high-protein supplement with fiber. Participants f…

This study looks at whether the ammonia in your breath can help detect malnutrition. Researchers will take breath and blood samples from 12 adults, some with and some without malnutrition, and compare the results. A small group will also drink special beverages and fast for two d…

This study aims to find out how common malnutrition is among hospital patients in China, Europe, and the USA. It will also look at whether providing nutrition support to those at risk improves their health outcomes and is cost-effective. Researchers plan to enroll 2,000 patients …

This study follows 48 adults with active Crohn's disease or ulcerative colitis who are starting biologic or JAK inhibitor therapy. Researchers use a quick, painless bioelectrical impedance scan to measure muscle mass and other body composition changes at the start, 24 weeks, and …