SARCOPENIA

This study is for adults with end-stage liver disease who are waiting for a liver transplant. It compares three approaches: a diet with protein spread evenly across meals plus exercise, a diet with protein mostly at one meal plus exercise, or standard advice. The goal is to see w…

This study tests a new clinic designed to find and treat muscle loss (sarcopenia) in people with COPD. About 80 adults hospitalized for COPD will join a team of lung doctors, nurses, and a pharmacist who will use CT scans and other tests to diagnose muscle loss and provide target…

This study tests a digital therapeutic device (exoDTx) to see if it improves muscle strength more than self-exercise in people with sarcopenia, a condition causing age-related muscle loss. About 130 participants will use the device or exercise on their own for 12 weeks. The main …

This study tests whether a drug called nandrolone decanoate, combined with physical therapy and a special diet, can help older adults with sarcopenia (age-related muscle loss) regain strength and mobility. About 168 people aged 60 to 99 will receive either the drug or a placebo, …

This study tests a 12-week exercise program for adults aged 45 to 85 who have both type 2 diabetes and sarcopenia (age-related muscle loss). The program combines supervised and home-based exercises with digital support to improve muscle strength, physical function, and blood suga…

This study looks at whether taking krill oil for 6 months can increase muscle strength and improve walking in healthy adults aged 65 and older. Researchers will measure grip strength, leg muscle size, and how well nerves control muscles. The goal is to find out if a simple supple…

This study tests a prehabilitation program for adults aged 65 and older with breast cancer. The program includes exercise, nutrition advice, and a health assessment before surgery. The goal is to see if it helps maintain physical function and reduce complications. Researchers wil…

This study looks at people with cirrhosis (scarred liver) who also have severe muscle loss (sarcopenia) and need a procedure called TIPS to treat complications like bleeding. Half will get standard care, and half will also take branched-chain amino acid (BCAA) supplements for 6 m…

This study tests whether a virtual group exercise program combined with health education can lower fall risk and increase physical activity in older veterans who have both obesity and signs of muscle loss (sarcopenia). About 50 veterans aged 55 and older will take part. The goal …

This study tests whether taking creatine HCl daily for 12 weeks can improve muscle strength, physical function, and brain performance in adults over 60 with sarcopenia (age-related muscle loss). Researchers will also check changes in blood markers and tissue creatine levels. The …

This study looks at whether high-intensity interval training (HIIT) or moderate continuous exercise is better at rebuilding muscle and improving function in people who have had a stroke and suffer from muscle loss (sarcopenia). About 32 adults who had a stroke 1-6 months ago will…

This study tests whether taking vitamin D after surgery helps maintain muscle health and speed recovery. Researchers will measure vitamin D levels in 100 adults aged 21-65 over 12 months. The goal is to see if a specific supplement plan works better than standard care.

This study looks at whether taking creatine supplements while doing supervised resistance training for 12 weeks can help men with prostate cancer who are on hormone therapy (ADT) maintain or improve their muscle mass, strength, and physical function. ADT often causes muscle loss …

This study tests whether adding a blood-filtering device called CytoSorb to standard care can help people with acute-on-chronic liver failure. The device aims to remove harmful substances like bilirubin and ammonia from the blood. Twenty adults with severe liver failure will rece…

This study tests a new way to diagnose sarcopenia—a condition where older adults lose muscle mass and strength, raising their risk of falls and disability. Researchers will use a high-definition muscle sensor (HD-sEMG) to see if it can tell who has sarcopenia better than current …

This study tests whether measuring calf circumference with a tape measure can accurately diagnose sarcopenia (muscle loss) in hospitalized adults aged 75 and older. Researchers will compare the tape measure results to a standard X-ray method. If successful, this could offer a sim…

This study tests a 12-week program using a smartphone app (Line Bot) that provides personalized exercise videos, nutrition tips, and daily reminders for older adults at risk of sarcopenia (muscle loss). Sixty participants will be split into two groups: one using the app, the othe…

This study tests whether taking essential amino acid supplements and doing exercise can improve muscle strength and function in people on hemodialysis who have muscle loss (sarcopenia). About 40 participants will be randomly assigned to receive the supplements plus exercise or st…

This study tests whether adding electroacupuncture to standard rehabilitation helps elderly people with sarcopenia (age-related muscle loss) walk farther and move more easily. Researchers will enroll 120 people aged 60–95 and randomly assign them to receive either electroacupunct…

This study looks at whether a pulmonary rehabilitation program can help people with advanced non-small-cell lung cancer maintain muscle mass, improve lung function, and reduce inflammation. About 94 participants will take part while receiving standard cancer treatments like chemo…

This study looks at whether a supervised exercise program with resistance training and relaxation can help breast cancer survivors build muscle and improve their quality of life. About 66 people who have finished treatment for early-stage breast cancer will take part. They will e…

This study tests whether taking silkworm pupa powder daily for 3 months can improve the nutritional health, muscle strength, and quality of life of people with Alzheimer's disease. Researchers will compare the powder to a placebo in 200 participants aged 50-90. The goal is to see…

This small study tests whether a physical activity program can help children (ages 5-17) with acute lymphoblastic leukemia maintain or regain muscle strength during early treatment. Kids who show signs of weakness after 5 weeks of treatment are randomly assigned to either the exe…

This study tests whether taking a daily oil rich in linoleic acid can improve muscle strength, size, and endurance in older adults with sarcopenia (age-related muscle loss). Participants will consume 12 grams of safflower oil daily for several weeks. The goal is to see if this si…

This study tests whether a 6-week supervised pool exercise program can improve muscle strength, muscle mass, physical performance, and quality of life in adults aged 65 and older with sarcopenia (age-related muscle loss). Participants will exercise in water, which is easier on jo…

This study tests whether a 12-week supervised exercise program done during dialysis can improve muscle mass, strength, sleep, and quality of life in adults over 40 with chronic kidney disease. Participants are randomly assigned to either an exercise group or standard care. The go…

This study explores whether taking a daily polyphenol supplement (natural compounds found in plants) alongside a 12-week exercise program can help older adults build strength and physical function better than exercise alone. Researchers will recruit 40 people over 60 to test if t…

This study tests a rehabilitation program combining daily low-flow dialysis with exercise and nutrition monitoring for kidney patients who recently left the hospital. The goal is to improve muscle strength and physical function, which often decline in people on standard dialysis.…

This study looks at whether whole body vibration therapy, when added to usual care, can improve muscle mass, strength, and function in older adults. Forty people aged 65 and older with mild frailty will be randomly assigned to receive vibration therapy plus usual care or usual ca…

This study tests whether adding electrical muscle stimulation (EMS) to lower-body exercises helps postmenopausal women improve muscle strength and artery health more than exercise alone. About 39 women aged 50-70 who do not currently exercise will be split into three groups: EMS …

This study looks at how a special MRI scan can measure muscle health in people with heart failure who also have muscle loss (sarcopenia). Researchers will scan 70 adults—some with heart failure and sarcopenia, some without—to compare muscle changes. The goal is to find better way…

This study looks at the gut bacteria of older adults with sarcopenia (age-related muscle loss) and compares them to healthy older and young adults. Researchers want to find differences that could help create probiotics to treat sarcopenia. The study involves 150 participants and …

This study looks at whether sarcopenia (age-related muscle loss) is linked to the type and location of rotator cuff tears in people with shoulder pain. Researchers will measure muscle strength and thigh thickness in 104 adults aged 40-75, then compare shoulder MRI scans. The goal…

This study looks at why some older adults get more benefits from exercise than others. Researchers will have 250 people aged 60+ follow a combined endurance and resistance training program. The goal is to understand the differences in how people respond, so that in the future exe…

This study looks at how common muscle loss and weakness are in people with liver cirrhosis, and how malnutrition plays a role. Researchers will use ultrasound and grip strength tests to track changes over two years. The goal is to better understand these problems to improve futur…

This study aims to find out how common malnutrition and muscle loss (sarcopenia) are among adult outpatients in Turkey. Researchers will screen 7,500 people aged 18 and older visiting hospital clinics for any reason. Participants answer a questionnaire and have simple measurement…

This study looks at whether women with gestational diabetes (diabetes during pregnancy) also have sarcopenia, a condition of muscle loss and weakness. Researchers will check 200 pregnant women for sarcopenia and follow their pregnancy outcomes and thinking abilities. The goal is …

This study is following 10,000 adults aged 18 and older to learn how muscle loss (sarcopenia), metabolic diseases, and aging are connected. Researchers will collect health data, lifestyle info, and biosamples over time. The goal is to understand what leads to earlier death and po…

This study looks at whether a 2-week program of exercise and nutrition before head and neck cancer surgery is safe and acceptable. Researchers will track how many patients complete the program, any side effects, and how well participants follow the plan. The goal is to see if thi…

This small pilot study tests whether whole-body electrical muscle stimulation combined with exercise can improve the way nerves activate muscles in healthy older adults (65+). Participants will do supervised sessions twice a week for four weeks, with before-and-after tests of mus…

This study looks at how well a new type of whey protein, called 'super-whey', helps older adults build muscle. Researchers will give 30 participants different doses of the protein and measure muscle growth at rest and after exercise. The goal is to find the best dose to fight age…

This study looks at how nutrition and body composition (like muscle mass) influence treatment results in people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 300 patients starting new medical therapies or undergoi…

This study looks at whether older adults with advanced colorectal cancer who have low muscle mass are more likely to have severe side effects from chemotherapy. Researchers will follow 300 people starting treatment to track side effects and survival. The goal is to better underst…

This study looks at how vegetarian and plant-based diets affect healthy aging in 5,000 middle-aged and older adults in Taiwan. Researchers will measure thinking skills, muscle mass, and strength to see if these diets help prevent age-related problems like frailty and memory loss.…

This study is enrolling 20,000 adults in Taining County, China, to better understand common chronic diseases like high blood pressure, diabetes, and frailty. Researchers will collect health data and samples over three years to find patterns and risk factors. The goal is to create…

This study follows 250 adults in the intensive care unit (ICU) to learn why some become frail and lose muscle. Researchers will track hospital stays, falls, and readmissions to find factors that can be changed. The goal is to identify targets for future treatments to help patient…

This study looks at why people with chronic kidney disease (CKD) often lose muscle mass and strength, a condition called sarcopenia. Researchers will follow 1,000 adults with CKD to find risk factors for sarcopenia and see how it affects their health over time. The goal is to bet…

This study aims to validate and check the reproducibility of laboratory tests, equipment, and techniques used in research on chronic diseases like obesity, diabetes, and heart disease. Researchers will compare old and new testing methods to ensure results are accurate and consist…

This study looks at how many people with gastrointestinal cancer are at risk for sarcopenia, a condition where muscle mass and strength are lost. Sarcopenia can make cancer treatment harder and lower quality of life. Researchers will use a simple questionnaire (SARC-F) to screen …

This study looks at whether the type of anesthesia used during colorectal cancer surgery affects how much muscle patients lose afterward. Researchers will measure muscle mass and strength in 40 adults using ultrasound, grip tests, and body composition scans. The goal is to find w…

This study looks at how diet and gut bacteria are linked to sarcopenia, a condition where older adults lose muscle mass and strength. Researchers will analyze the diets and gut microbes of 1,220 people aged 60 and older. The goal is to understand if certain foods that cause infla…

This study looks at how a person's muscle mass (fat-free mass) relates to side effects from standard chemotherapy (carboplatin/paclitaxel) in advanced non-small cell lung cancer. Researchers will track 132 participants to see if adjusting the chemo dose based on body composition …

This study looks at whether easy-to-do tests for muscle strength, breathing, and frailty can help predict complications after major abdominal surgery in people aged 65 and older. About 100 participants will complete these tests during a routine pre-surgery visit, and researchers …

This study looks at whether showing older adults with sarcopenia (age-related muscle loss) their movement speed during leg presses helps them activate muscles better and feel more motivated. Sixty participants aged 60-95 will visit the lab once a week for three weeks to do leg ex…

This study looks at muscle loss (sarcopenia) and cognitive problems (chemobrain) in people who have finished cancer treatment. Researchers will collect data from 100 adults aged 18-74 with certain cancers to understand how common these issues are. The goal is to improve support a…

This study is observing 142 adults having lung cancer surgery to see if their nutrition and muscle health can predict complications, hospital stay length, and survival. Researchers will use blood tests, CT scans, and ultrasound to measure these factors before surgery. The goal is…

This study follows 100 women who had breast cancer surgery and therapy to see how their muscle mass and body fat change over two years. Researchers will measure muscle strength and body composition regularly. The goal is to understand the long-term physical effects of cancer reco…

This study looks at why a common liver procedure called TIPS might help people with cirrhosis who have severe muscle loss (sarcopenia). Researchers will measure changes in a protein called FGF21 and muscle mass in 132 adults over one year. The goal is to understand the mechanism,…