Mind over muscle: imagining max effort may strengthen aging bodies
NCT ID NCT07687316
First seen Jul 07, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study tests whether combining low-intensity resistance training with maximal mental effort—imagining a full-force muscle contraction during each exercise—can improve strength and muscle function more than low-intensity training alone. Researchers will enroll 75 older adults with functional limitations and poor lower-body strength who have not exercised in the past two years. Participants are randomly assigned to one of three groups: low-intensity training, low-intensity training with mental effort, or a control group. The goal is to see if the mind-muscle connection can enhance physical gains without heavy lifting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low-intensity resistance training with maximal mental effort
- What this could lead to
- If it works, this approach could offer a simple, low-risk way to improve strength and physical function in older adults without heavy exercise.
- What could go wrong
- This is a small, early-stage trial. The mental effort technique may not produce meaningful physical gains, and results may not apply to all older adults.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Body mass index between 18.5 - 33 kg·m2 * No structured physical activity in past 2 years * Any unstable condition contradicting exercise * Independently walk with or without assistive device * No significant cognitive impairment Exclusion Criteria: * Score of 22 or lower on Montreal Cognitive Assessment * Missing more than 3 training sessions (training groups only) * Pacemaker * Unstable angina * Symptomatic heart failure * Uncontrolled arrythmias * Uncontrolled hypertension (greater or equal to 160/90) * Myocardial infarction in the past 6 months * Uncontrolled type 2 diabetes * Type 1 diabetes * Severe or unstable pulmonary conditions, * Currently on supplemental oxygen therapy * Severe hearing loss or visual impairment * Alzheimer's Disease or significant cognitive impairment * Stroke in the past 6 months or ongoing stroke-induced motor impairment * Any neurological (e.g., Parkinson's) condition affecting motor control * Undergoing chemotherapy * Surgery in past 6 months * Musculoskeletal injury in the past 6 months * Terminal illness * Stage 3 or greater chronic kidney disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kennesaw State University
RECRUITINGKennesaw, Georgia, 30144, United States
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