SARCOPENIA

This study tests whether combining high-protein supplements, mobility-based physical therapy, and neuromuscular electric stimulation can help older adults (60+) recover muscle mass, strength, and function after a long ICU stay. About 78 participants will receive the combination t…

This study tests whether walking in a robotic exoskeleton combined with mild electrical stimulation of the spinal cord can improve muscle and bone health in people with chronic spinal cord injury. Twenty-four participants will be randomly assigned to receive either real or sham s…

This study tests whether ready-to-eat retort meals based on the MIND diet can improve muscle health, thinking skills, and nutrition in 70 low-income Malaysian adults aged 60-84 who are at risk of food insecurity. Over 12 weeks, one group gets the meals while the other does not, a…

This study looks at whether a traditional Chinese medicine formula, Huangjing Yangji, combined with resistance band exercises, can help older adults with sarcopenia (age-related muscle loss) improve their physical function and strength. About 106 participants will take either the…

This study tests whether a volunteer-led lifestyle program can improve muscle mass, strength, and mobility in older adults with or at risk of sarcopenia (age-related muscle loss). Two hundred people aged 60 and older will be randomly assigned to the program or usual care. The pro…

This study looks at whether a special exercise program (Phase I cardiac rehab) can help elderly people who have both heart disease and muscle loss (sarcopenia). About 100 participants will either get the rehab plus standard care, or standard care alone for 3 months. Researchers w…

This study tests whether a digital prehabilitation app (HEAL-ME) combined with creatine and whey protein supplements can help maintain muscle health and reduce frailty in people with cirrhosis. About 100 participants will use the app and take supplements for at least 3 months. Th…

This study tests different combinations of diet, extra protein, and resistance exercise to help 250 adults aged 50-75 with obesity lose weight while keeping muscle. Participants will follow a personalized plan over 52 weeks. The goal is to find the best approach for healthy weigh…

This study looks at whether roxadustat, a drug used to treat anemia in kidney disease, can also help reduce muscle loss (sarcopenia) in people on hemodialysis. About 60 adults with end-stage kidney disease and anemia will receive either roxadustat or standard treatment. Researche…

This study will develop an artificial intelligence tool to diagnose sarcopenia, a condition where older adults lose muscle mass and strength. Researchers will collect data from 75 people aged 65 and older with declining muscle function. They will also test whether a rehabilitatio…

This study tests a home strengthening program for adults aged 65 and older who have sarcopenia (muscle loss) or frailty. Participants use a Bluetooth-connected resistance band and app that gives real-time feedback, while a doctor monitors progress remotely. The goal is to see if …

This study tests whether personalized food and cooking advice can help slow muscle loss in adults with advanced cancer who are on chemotherapy. About 200 participants will either receive standard nutrition care or the same care plus tailored guidance based on their taste changes …

This study looks at whether a 12-week strengthening exercise program can improve muscle strength, muscle mass, and thinking abilities in people with compensated liver cirrhosis. Twenty participants will be randomly assigned to either face-to-face or home-based exercise. The goal …

This study will test whether interactive video-game exercises can improve foot muscle function, balance, and mobility in older adults. Forty healthy seniors aged 65-80 will be randomly assigned to either the exergame program or standard balance exercises for 8 weeks. Researchers …

This study tests a 12-week home-based exercise program for adults aged 60+ with type 2 diabetes and early muscle weakness (probable sarcopenia). Participants will do short bouts of aerobic and resistance exercises to see if it improves their physical activity levels and muscle st…

This study tests whether an 8-week tele-rehabilitation program can improve muscle mass, reduce frailty, and enhance quality of life in adults with cystic fibrosis. Participants will do supervised exercise sessions from home three times a week. The goal is to see if remote trainin…

This study tests whether two types of amino acid supplements can safely improve muscle mass and strength in 20 adults aged 45–75 with advanced chronic kidney disease and muscle loss (sarcopenia). Participants will take the supplements for 6 weeks each, and researchers will measur…

This study looks at whether two different exercise programs can improve physical function, balance, and mental well-being in older adults aged 60 and over living in Angola. A total of 350 participants will be randomly assigned to either a multicomponent exercise program or a simp…

This study tests whether using a health app for symptom tracking plus a resistance exercise program can improve quality of life and reduce muscle loss in people who had surgery for esophageal cancer. About 90 adults who have fully recovered from surgery will be enrolled. The goal…

This study tests whether a 32-week multicomponent exercise program can improve muscle quality, strength, and physical function in women over 60 with sarcopenia. Participants will undergo ultrasound measurements and strength tests. The goal is to see if exercise can reduce muscle …

This study tests whether adding neuromuscular electrical stimulation to resistance exercises can improve leg strength and physical function in hospitalized adults (ages 47-70) with alcoholic liver cirrhosis and muscle wasting (sarcopenia). Participants will be randomly assigned t…

This study tests a 6-week program combining group reading discussions with simple mouth exercises for adults aged 55 and older. The goal is to see if this non-drug approach can reduce depression, improve physical and oral health, and build mental toughness. Sixty participants wil…

This study looks at whether taking magnesium supplements can improve muscle strength, muscle mass, and physical performance in older adults with sarcopenia (age-related muscle loss). Researchers will enroll 352 people aged 70 and older in Portugal. Participants with low magnesium…

This study tests whether a supplement made from apple pomace (a byproduct of juicing) can improve muscle strength and physical function in older adults with mild sarcopenia, an age-related muscle loss condition. About 105 people aged 65-80 will take either a low or high dose of t…

This study tests a device that sends mild electrical pulses to the thigh muscles of people in the intensive care unit (ICU). The goal is to see if it is safe and practical to use, and whether it can help prevent muscle weakness that often happens during long ICU stays. About 50 a…

This study looks at whether a structured exercise program can help women who have had breast or gynecological cancer and now have weak muscles (sarcopenia). The goal is to see if exercise can improve muscle strength, muscle mass, physical function, and quality of life. About 78 w…

This study observes 30 adults in Mexico who are already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans, heart CT scans, and body composition tests to see how the drug affects knee cartilage, heart fat, and overall body health over one y…

This study will measure how many people with knee osteoarthritis also have sarcopenia (age-related muscle loss). Researchers will assess muscle mass, strength, and physical performance in 224 adults aged 40 and older in Upper Egypt. They will also look at nutrition and quality of…

This study looks at how muscle loss (sarcopenia) relates to tiredness and dizziness when standing up in people aged 65 and older. Researchers will compare 90 older adults with and without muscle loss to see if those with weaker muscles feel more tired or dizzy. The goal is to hel…

This study looks at how HIV might speed up aging. Researchers will compare frailty, muscle loss, nutrition, thinking, and physical function in 80 adults aged 40 and older—half with HIV and half without. The goal is to understand if people with HIV face these age-related problems …

This study will follow 110 patients aged 80 and older who are hospitalized for acute heart failure. Researchers will use muscle ultrasound, strength tests, and blood markers to understand how muscle loss (sarcopenia) affects their recovery. The goal is to find better ways to pred…

This study looks at whether older adults (70+) with low muscle mass have a higher risk of bleeding while taking common blood thinners. Researchers will compare muscle mass, sarcopenia, and nutrition between 110 patients who had a bleeding event and those who did not. The goal is …

This study watches how sarcopenia (muscle loss) and frailty affect the drug rocuronium, a muscle relaxant used during surgery, in 100 older adults. Researchers will measure how fast the drug works and how long it lasts. The goal is to help doctors give safer anesthesia to elderly…

This study looks at 100 elderly patients with hip fractures to see if easy, quick tests like muscle ultrasound, handgrip strength, and routine blood work can predict frailty. Frailty affects recovery after surgery, so finding a fast way to measure it could help doctors plan safer…

This study looks at why childhood cancer survivors often lose muscle mass and strength earlier than normal. Researchers will use advanced scans and tests to compare survivors with and without muscle problems to healthy adults. The goal is to find different types of muscle decline…

This study looks at whether a routine CT scan can tell doctors which patients with leg artery disease (PAD) will get better with exercise therapy. About 40% of patients don't improve with exercise and need a procedure to open blocked arteries. Researchers will measure muscle qual…

This study will measure how common muscle loss (sarcopenia) is in 100 older adults aged 60+ who have had type 2 diabetes for at least 5 years. Researchers will use ultrasound and grip strength tests to assess muscle health and a questionnaire to see how muscle loss affects qualit…

This study looks at whether measuring fat inside the muscles with ultrasound can help predict how well older adults recover physical function after a hospital stay. Researchers will follow 115 people aged 75 and older in a rehabilitation program. No treatment is given; the goal i…

This study looks at whether combining simple tests—handgrip strength, electrical body scans, and thigh ultrasound—can help doctors spot rapid muscle loss (acute sarcopenia) in older adults admitted to the hospital. Researchers will follow 280 patients aged 65 and older to find ou…

This is a randomized, double-blind, placebo-controlled, parallel-group, prospective, multi-center clinical trial, to evaluate the efficacy of silkworm pupa tablets in improving nutritional status and sarcopenia in patients with malignancies who have completed comprehensive treatm…