Routine CT scan may reveal who needs surgery instead of exercise for leg pain

NCT ID NCT07433309

Not yet recruiting Knowledge-focused Sponsor: Nemocnice AGEL Trinec-Podlesi a.s. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a CT scan already done for routine care can predict which patients with leg artery disease will improve with supervised exercise therapy. About 40% of patients don't get enough benefit from exercise and need a procedure to open blocked arteries. Researchers will measure muscle quality and belly fat from the CT scan and see if these factors predict exercise success in 128 participants over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: supervised exercise therapy (SET)
What this could lead to: If successful, this could allow doctors to use a routine CT scan to identify which patients are unlikely to improve with exercise, helping them choose the right treatment sooner.
What could go wrong: This is an early-stage observational study, not a treatment trial. It may not confirm that CT scans reliably predict exercise response, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

intermittent vascular claudication peripheral arterial disease Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BODY COMPOSITION PERIPHERAL ARTERIAL DISEASE SARCOPENIA SARCOPENIC OBESITY

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