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Calf power may hold the key to healthy aging – a study investigates

NCT ID NCT07726498

Knowledge-focused Sponsor: University of Leicester Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study examines whether calf muscle strength, measured with commercially available equipment, can identify adults at risk of sarcopenia (age-related muscle loss) and falls. Researchers will compare strength tests, walking patterns, and body composition in 200 adults aged 18 and older, both with and without sarcopenia. The goal is to find simple, practical ways to spot mobility decline early.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to simple, clinic-friendly tests to identify people at risk of falls and muscle loss due to aging.
What could go wrong
This is an observational study, not a treatment trial. It will measure associations, not prove cause and effect. Results may not change clinical practice directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population is individuals over the age of 18 years, who may or may not have sarcopenia. Individuals will be determined as either sarcopenic or non-sarcopenic by completing the outcome measures (SARC-F questionnaire, Grip strength, BIA and SPPB) and using the cut-off values as recommended by the European Working Group on Sarcopenia in Older People 2 consensus.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant is able and willing to provide informed consent to participate in the study * Aged 18 years or over * Ambulatory status: able to walk independently with or without aids * Able to attend clinic Exclusion Criteria: * Participant is unwilling or unable to give informed consent. * Palliative/ end of life * Moderate to severe communication difficulties/ cognitive function * Immobile * Lower limb surgery within the last 6 months * Recent lower limb fracture * Unstable cardiopulmonary conditions * Severe impairments of vision or vestibular system * Lower limb corticosteroid injection within the last 6 months * No restriction on language

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Conditions

The condition(s) this trial relates to.

Asthenia Atrophy Frailty Muscle Weakness Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Frailty Muscle weakness or atrophy Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Leicester

    Leicester, LE1 7RH, United Kingdom

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