SARCOPENIA

This study tests whether 12 months of high-intensity strength training can reduce falls in people aged 80 and older who have sarcopenia (age-related muscle loss). About 241 participants will either do progressive resistance exercises or be in a control group. The goal is to see i…

This study looks at whether giving extra nutrition through a vein during dialysis (called IDPN) helps kidney patients maintain muscle mass and improve their quality of life. About 166 adults on long-term dialysis will receive IDPN or standard care. The main goal is to see if it p…

This study tests whether taking branched-chain amino acid (BCAA) supplements for 24 weeks can help people with liver cirrhosis who have low muscle mass (sarcopenia) regain muscle and improve their health. About 86 participants will receive either BCAA or a placebo, along with die…

This program provides expanded access to an experimental treatment called IMM01-STEM for people with sarcopenic obesity—a condition where both muscle loss and excess body fat occur. It is designed for patients who cannot participate in other clinical trials due to eligibility, lo…

This study looks at 60 people with advanced esophageal cancer who are getting chemotherapy or radiation before surgery to remove the cancer. Some patients had a feeding tube placed early, at the time of diagnosis, while others had it placed later during surgery. The goal is to se…

This study tests whether eating special biscuits made with pea protein and taking vitamin D can slow or prevent sarcopenia (age-related muscle loss) in adults aged 65-80. Over 12 weeks, 74 volunteers will eat either the protein biscuit plus vitamin D or a regular biscuit with a p…

This study looks at whether taking creatine and HMB (a protein-like supplement) along with a supervised exercise program can improve physical function, muscle mass, thinking skills, and quality of life in frail older adults living in nursing homes. Fifty people aged 65 and older …

This study was designed to see if a 6-month nutrition plan can help malnourished older adults gain weight and strength compared to standard hospital care. It included people aged 65 and older who were malnourished. The study was withdrawn before enrolling any participants, so no …

This study looks at whether doing light exercise during dialysis sessions can help people with advanced kidney disease who also have muscle loss (sarcopenia). About 40 adults will either exercise three times a week during dialysis or continue their usual care. Researchers will me…

This study looks at whether a 12-week program of functional task training (like standing up, walking, and carrying objects) can improve muscle strength and daily function in older adults with sarcopenia. 30 people aged 60 and older will be randomly assigned to different exercise …

This study looks at whether a group exercise program using videos is safe and doable for people with kidney failure who are on dialysis. The goal is to help them keep muscle strength and function, which often gets worse during treatment. About 45 adults will try the program durin…

This study tests whether a daily vitamin B3 supplement called nicotinamide riboside can improve muscle strength, walking speed, and endurance in older veterans aged 65-85. Participants take the supplement or a placebo for a period and undergo exercise tests and muscle biopsies. T…

This study is testing whether artificial intelligence can better predict who is at risk for sarcopenia—the age-related loss of muscle mass and strength. Researchers will first analyze data from 3,500 adults to build a risk model, then test a personalized 12-week exercise and nutr…

This study looks at how common muscle loss (sarcopenia) is in adults who need a breathing machine for more than 48 hours in the intensive care unit. Researchers will use simple tests like questionnaires, body composition scans, and ultrasound to measure muscle changes. The goal i…

This study measures how much force leg muscles can produce and how they use oxygen in people who have had a stroke or have sarcopenia (age-related muscle loss). Researchers will test hip, knee, and ankle strength at different angles and speeds. The goal is to use this data to des…

This study looks at 200 adults with solid tumors who are getting chemotherapy. Researchers are comparing four different checklists (PG-SGA, MUST, Nutriscore, and GLIM criteria) to see which one best identifies malnutrition and muscle loss. The goal is to find the most reliable sc…

This study looks at whether watching short, educational videos (nano-learning) can help older adults with sarcopenia (age-related muscle loss) stick to diet and exercise advice and improve their mood. Researchers are testing this approach with 180 people aged 60 and older in a ru…

This study looks at whether common osteoporosis medications also improve muscle health in adults aged 65 and older who have both osteoporosis and low muscle mass (sarcopenia). Researchers will measure changes in muscle mass, strength, walking speed, and bone density over time. Th…

This study looks for better ways to detect muscle loss (sarcopenia) in people with heart failure. Many heart failure patients also have muscle loss, which makes their condition worse. Researchers will measure muscle mass, strength, and walking speed in 80 adults aged 50 and older…

This study re-examines 317 adults with type 2 diabetes who were first checked for fatty liver disease a few years ago. Researchers will use advanced scans and blood tests to see if their liver condition has improved, worsened, or stayed the same. The goal is to find patterns and …

This study looks at how well certain tools measure muscle strength and activity in people with chronic kidney disease. It also tests whether a supervised online exercise program is helpful and practical. About 50 adults with kidney disease (on dialysis, with a transplant, or not …

This study looks at muscle and fat in people with chronic kidney disease (CKD) compared to healthy volunteers. The goal is to understand when and how muscle loss happens in CKD, so future treatments can improve quality of life. About 80 adults with and without CKD will take part.

This study is looking at whether having low muscle mass (sarcopenia) before lung cancer surgery affects how well patients recover. Researchers are following 400 older adults who are having surgery to remove lung cancer. They want to see if muscle loss can help predict survival an…

This study looks at how much muscle loss and fatigue breast cancer patients experience during and after radiation therapy. Researchers want to see if muscle loss happens in areas not directly treated by radiation, and whether it's linked to how tired patients feel. Twenty women w…

This study measures muscle mass, strength, and calf size in healthy Turkish adults aged 18-39 and 65-99. The goal is to create reference values specific to the Turkish population, so doctors can more accurately diagnose sarcopenia—a condition of muscle loss that raises the risk o…