Supplements and exercise: a new hope for frail seniors?
NCT ID NCT07275996
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding creatine and HMB supplements to a supervised exercise program can improve physical function, muscle mass, thinking skills, and quality of life in frail older adults living in nursing homes. Fifty people aged 65 and older are taking part, receiving either placebo, creatine, HMB, or both, plus exercise, for 12 weeks. The goal is to find a practical way to help seniors stay stronger and more independent.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- creatine monohydrate and β-hydroxy-β-methylbutyrate (HMB) dietary supplements
- What this could lead to
- If it works, this could point toward a simple, affordable supplement-plus-exercise strategy to help frail older adults maintain strength, mobility, and independence.
- What could go wrong
- This is a small, early-stage trial with only 50 participants, so results may not apply to all older adults. Supplements may have no added benefit over exercise alone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Residencia de Mayores Fuentes Blancas (Diputación Provincial de Burgos)
Burgos, Castille and León, 09002, Spain
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