Nutritional deficiency disease

This pilot study tests whether giving special nutritional shakes before and after surgery can improve the health of patients with critical limb ischemia, a severe form of peripheral artery disease. About 30 participants will drink the shakes for one to two weeks before and after …

This study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…

This study tests an injectable form of choline, a nutrient often missing in people with intestinal failure who rely on IV nutrition. The goal is to see if it can safely raise choline levels and reduce liver injury. About 129 adolescents and adults will receive either a low or hig…

This study tests whether adding calcitriol to vitamin D2 helps children with cholestatic liver disease correct their vitamin D deficiency faster than vitamin D2 alone. Cholestasis makes it hard for the body to absorb vitamin D. The trial will enroll 54 children and track vitamin …

This study compares IV iron to oral iron pills for treating moderate anemia after a C-section. The goal is to see if better iron levels can reduce the risk of postpartum depression. About 2,860 women will take part, and their mood will be checked 8 weeks after delivery.

This study tests whether a special medical food called LH VIOLA, taken as a partial replacement for regular meals, can help people with Crohn's disease or ulcerative colitis who are at risk of malnutrition maintain or regain weight and muscle strength. About 146 participants will…

This study tests whether a simple text-message system can help caregivers in Kenya spot and prevent malnutrition in children exposed to HIV. About 776 caregiver-child pairs will be split into two groups: one gets weekly SMS reminders to measure the child's arm and receive feeding…

This study tests whether giving DHA (a type of omega-3 fat) early to very preterm infants who are small at birth can improve head growth without causing too much fat gain. The trial will include 152 infants and measure head size and body fat at 36 weeks adjusted age. If successfu…

This study tests whether a low-dose liposomal iron supplement works better and causes fewer stomach issues than the standard high-dose iron pills for people with iron deficiency anemia after sleeve gastrectomy. About 70 adults who had this weight-loss surgery at least 6 months ag…

This study looks at whether vitamin D levels and supplements can reduce inflammation in people with gum disease (periodontitis or gingivitis). Researchers will measure markers of inflammation in blood and gum fluid before and after treatment. The study involves 120 adults with di…

This study tests a program that combines face-to-face counseling with a mobile app to help teenage girls with iron deficiency anemia. About 160 girls aged 14-17 with low iron levels will either get the program or standard care. The goal is to see if the program raises their hemog…

This study tests whether a structured, tailored nutritional care program helps children who need nutritional support after leaving the hospital. About 260 children from newborns to 18 years old will take part. Parents fill out questionnaires on eating behavior, stress, and food d…

This study tests whether giving a combination of iron, erythropoietin, and vitamin C before major heart surgery can lower the need for blood transfusions in adults with iron-deficiency anemia. About 400 participants will receive either the combined regimen or standard care. The g…

This study looks at whether giving patients with bone or soft tissue sarcoma a special nutritional supplement twice daily before surgery can reduce complications and help maintain muscle mass. About 100 adults scheduled for tumor removal will be randomly assigned to receive eithe…

This study tests whether giving preterm babies (born before 32 weeks) a drug called darbepoetin plus a slow-release intravenous iron can reduce the need for blood transfusions, keep their iron levels healthy, and improve their brain development. About 120 infants will be enrolled…

This study tests a program that gives food supplements to pregnant women, new mothers, and their babies, along with advice on healthy eating, exercise, and infant feeding. The goal is to reduce both maternal obesity and child stunting in rural Indigenous communities in Guatemala.…

This study tests whether giving vitamin A supplements to children with low vitamin A levels can slow the worsening of scoliosis (curved spine). The trial will include 140 children aged 6 to 15 who have mild to moderate scoliosis and are still growing. Half will get vitamin A plus…

This study looks at whether giving iron supplements to children with low iron before hip surgery can reduce their need for blood transfusions and improve recovery. The trial includes 180 children aged 0-18 who are scheduled for a specific type of hip surgery, many of whom have ce…

This study looks at different ways to give iron to people with kidney failure who are on peritoneal dialysis. Participants will get either high-dose or low-dose intravenous iron, or oral iron tablets. The main goal is to see if a larger trial is possible by checking how many peop…

This study tests whether a high-energy liquid formula with added vitamins can improve nutrition in children under 5 who have chronic cholestasis (a liver condition that blocks bile flow) and severe malnutrition. Fifteen children will drink the formula for 14 days, and researchers…

This study tests whether a special type of iron supplement (Sucrosomial iron) helps children with celiac disease who also have low iron or anemia. The trial will compare children who take the supplement plus a gluten-free diet to those who only follow the diet. The goal is to see…

This study looks at whether eating protein evenly throughout the day, combined with a regular exercise program, can improve nutrition, muscle mass, and strength in people with end-stage liver disease awaiting a transplant. 90 participants will be split into three groups: one with…

This study tests whether giving intravenous iron to older adults (70+) after heart surgery helps them recover from anemia and reduces disability. About 310 patients will receive either iron or a placebo. The main goal is to see if iron improves daily functioning 90 days after sur…

This study tests whether taking an iron pill every other day works as well as taking one daily for pregnant women with iron-deficiency anemia. About 120 pregnant women with low iron will be randomly assigned to one of two schedules. The goal is to see if both approaches can raise…

This study tests a medicine called ferumoxytol, given as an IV infusion, to treat iron deficiency anemia in children aged 2 to 17. It is for kids who cannot take or do not respond to oral iron supplements. The main goal is to see if it safely raises hemoglobin levels after 5 week…

This study tests a drug called ferumoxytol, a type of intravenous iron, to treat iron deficiency anemia in children aged 2 to 17 with chronic kidney disease. The trial compares ferumoxytol to another iron drug, iron sucrose, to see which is safer and works better. About 129 child…

This study tests an intravenous iron medicine (ferric derisomaltose) in 200 children aged 0 to 18 who have iron deficiency anemia due to chronic kidney disease or who cannot take or do not respond to oral iron. The goal is to see if one or two doses can raise hemoglobin levels sa…

This study looks at whether taking vitamin D supplements during standard chemotherapy can help more tumors disappear in people with triple-negative breast cancer who are low in vitamin D. About 50 participants will receive vitamin D plus chemotherapy, and researchers will compare…

This study looks at whether giving anemic patients a combination of iron, erythropoietin, and vitamin C for three days before heart surgery can improve their quality of life, sleep, and fatigue over the long term. Researchers will compare these patients to those receiving standar…

This study tests whether working through existing community groups can increase the number of children with severe acute malnutrition (SAM) who get proper treatment. Researchers will enroll 1,080 children aged 6-59 months in Ethiopia and measure how many receive care. The approac…

This study looks at whether training local health workers to screen children for severe wasting and remind caregivers to measure their child's arm can get more kids the treatment they need. About 1,600 children in Turkana, Kenya, will take part. The goal is to see if this simple …

This study tests a new way to help doctors in Mozambique and Zambia decide if a sick child has tuberculosis (TB). The approach uses simple checklists and decision guides, supported by a computer system, to improve diagnosis and treatment, especially for children with HIV or sever…

This study tests two oral iron supplements, Sucrosomial® Iron and Ferric Maltol, in 146 women with mild to moderate iron deficiency anemia. The goal is to see if Sucrosomial® Iron works as well as Ferric Maltol at raising hemoglobin levels after 12 weeks, while causing fewer stom…

This study tests whether adding choline to a peanut-based therapeutic food improves cognitive development in 1,500 Malawian children aged 6-59 months with severe acute malnutrition. Half get standard food, half get food with extra choline. All also receive amoxicillin. The goal i…

This study tests whether daily high-calorie nutritional supplements can improve growth and development in 200 malnourished children aged 1 to 3 years. One group gets the supplements plus nutrition education, while the other gets only education and diet advice. Researchers will me…

This study looks at whether a plant-focused diet can help malnourished adults on peritoneal dialysis (a type of kidney treatment) improve their nutrition and overall health. About 100 participants will be randomly assigned to either a plant-focused diet or a standard kidney diet …

This study tests whether giving ICU patients extra protein and activating their muscles early (using electrical stimulation and movement) can prevent severe muscle loss. About 40 critically ill adults on ventilators will take part. The goal is to see if this approach helps patien…

This study tests whether taking vitamin D daily for 6 months can improve menstrual regularity and mood in teenage girls with PCOS who also have low vitamin D levels. Sixty participants will be randomly assigned to receive either vitamin D or a placebo, and neither they nor their …

This study looks at whether giving vitamin C alongside standard hospital care can help children under five with severe pneumonia recover faster. Ninety children will be split into two groups: one gets standard treatment alone, the other gets standard treatment plus a daily dose o…

This study is testing a new protein drink (AYMES Protein Shot) in 40 adults with or at risk of malnutrition due to illness. The goal is to see if the drink is easy to take, tastes good, and causes any stomach issues. Participants will use the product for 28 days and report their …

This study tests whether a daily supplement containing vitamin D, EGCG (from green tea), D-chiro-inositol, and vitamin B6 can shrink uterine fibroids in women who are eligible for surgery. Sixty women will take either the supplement or a placebo for three months. The main goal is…

This study tests whether giving iron through a vein (IV) after heart surgery helps people with iron-deficiency anemia recover better. About 60 adults having planned open-heart surgery will receive either IV iron or a placebo. The goal is to see if this treatment is practical and …

This study aims to reduce food insecurity by providing plant-based food prescriptions to 100 low-income families. Participants will track their intake of fruits, vegetables, whole grains, legumes, and nuts/seeds. The goal is to improve access to healthy food and nutrition knowled…

This study tests whether giving iron through a vein can help people with pulmonary hypertension (high blood pressure in the lungs) who also have low iron levels. Many patients with this condition have trouble absorbing iron from pills. The trial will compare intravenous iron to a…

This study looks at whether adding regular exercise (treadmill walking) to vitamin D supplements can improve erectile function in men with type 2 diabetes who also have low vitamin D. Forty men will take vitamin D every two weeks for 12 weeks; half will also walk three times a we…

This study looks at whether helping families with food benefits can improve weight in infants who are already overweight and at risk for food insecurity. About 228 infants aged 12 months and their parents will get $50 per week for one year, either as cash or as guided grocery sho…

This study compares two different vitamin D3 supplements to see which one raises vitamin D levels faster and more effectively in adults who are low in vitamin D. About 20 people will take one of the two supplements daily for eight weeks. The goal is to find the best way to correc…

This study tests whether taking an iron pill every other day works as well as taking one daily for adults with iron deficiency anemia. About 114 participants will be randomly assigned to one of two groups for 8 weeks. Researchers will check blood levels and side effects to see if…

This study looks at whether vitamin D supplements can help people with sarcoidosis who have low vitamin D levels. Researchers will give some participants vitamin D2 and others a placebo, then measure changes in lung function and quality of life. The goal is to see if correcting v…

This study tests whether early, personalized nutritional support and a simple home exercise program can prevent weight loss and improve quality of life in 200 adults with lung, colorectal, ovarian, or pancreatic cancer starting palliative chemotherapy. Participants receive guidan…

This study tests a new, personalized version of a weight-loss surgery called SADI-S. Surgeons will measure each patient's small intestine and adjust the bypass length to maximize weight loss while lowering the risk of vitamin deficiencies. The study includes 40 adults with obesit…

This study tests whether adding milk fat globule membrane (MFGM) to a standard therapeutic food helps brain development and reduces death or hospitalization in 1,600 severely malnourished children aged 6-59 months in Sierra Leone. Children receive either the MFGM-enriched food or…

This study tests whether giving iron through a vein (IV) early in the second trimester works better than iron pills for treating anemia in pregnancy. About 80 pregnant women with mild iron deficiency will be randomly assigned to one of the two treatments. The goal is to see which…

This study looks at how safe SMOFlipid is for children and adults who need IV nutrition for 8 weeks or more. It checks if the treatment causes a lack of essential fats or liver problems. About 100 participants will be followed to see how their bodies respond.

This study tests whether giving older patients at risk of malnutrition a food package, protein drinks, and dietitian support after hospital discharge can reduce readmissions and improve health. Researchers will enroll 2,000 patients aged 50 and older who are discharged with a lia…

This study tests whether giving intravenous iron to teens with iron deficiency before spinal fusion surgery can lower their need for blood transfusions. About 120 participants aged 10-19 will receive either IV iron or a placebo. The goal is to see if correcting iron levels improv…

This study looks at three different ways to take vitamin D in people with low levels. Participants will be randomly assigned to one of three groups: a monthly pill, a twice-monthly pill, or daily drops. After one month, researchers will measure vitamin D in the blood and check bo…

This study tests whether training caregivers to use a simple arm tape (mid-upper arm circumference) can detect malnutrition relapse in children who have recovered from severe acute malnutrition. About 2,400 children aged 6-54 months in Burkina Faso will be split into three groups…

This study is testing whether giving high doses of vitamin D3 to critically ill patients with very low vitamin D levels can reduce the chance of death within 28 days. The trial will include 2,400 adults in intensive care units. If successful, this cheap and easy treatment could b…

This study tests whether vitamin D3 supplements can improve heart health in Chinese teenagers who are overweight or obese and have low vitamin D levels. 130 participants will receive either vitamin D3 or a placebo for 12 weeks. Researchers will measure changes in blood pressure, …

This study tests whether a single dose of azithromycin helps children aged 6-59 months with severe acute malnutrition gain weight better than the standard 7-day amoxicillin course or a placebo. Researchers will enroll 3,000 children in Burkina Faso and track weight gain and nutri…

This study tests whether intravenous iron works better than oral iron pills for treating iron deficiency anemia in people who have had gastric bypass or sleeve gastrectomy surgery. About 104 participants will be randomly assigned to receive either a single IV dose of ferumoxytol …

This study tests whether a daily oral iron supplement (sucrosomial iron with vitamin C) can improve exercise ability and quality of life in people with chronic heart failure and iron deficiency. About 60 participants will receive either the iron supplement or a placebo for 24 wee…

This study tests whether a supervised exercise program combined with oral nutritional supplements can prevent disability in hospitalized adults aged 75 and older who are malnourished or at risk. Around 102 participants will be randomly assigned to either the exercise-plus-nutriti…

This study compares a plant-based high-energy, high-protein drink to a dairy-based version in 80 adults who are malnourished or at risk. Participants drink two servings daily for 8 weeks. Researchers track calorie and protein intake to see if the plant-based option works as well …

This study tests whether specialized bariatric supplements (Elan Believe, Compass, Supreme) prevent vitamin and mineral deficiencies after weight-loss surgery better than standard over-the-counter multivitamins. Over 600 adults undergoing sleeve gastrectomy, gastric bypass, or on…

This study in Burkina Faso and Pakistan will enroll 3,200 pregnant women to see if taking daily calcium and iron-containing multiple micronutrient supplements together is as effective as taking them at different times. The goal is to simplify supplement routines without harming t…

This study tests whether a daily multivitamin tablet can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like Ozempic or Saxenda) for weight loss. These drugs suppress appetite, which can lead to low nutrient intake. The trial will compare a multivitamin to …

This study follows 234 people who regained weight after a sleeve gastrectomy and are now getting a revision surgery. The goal is to compare three procedures—SADI-S, RYGB, and OAGB—to see which leads to the most weight loss, fewest complications, and best nutritional outcomes. Par…

This study looks at whether starting extra nutrition through an IV earlier (on day 4) versus later (on day 8) helps critically ill patients survive. About 946 adults with organ failure who cannot get enough nutrition from a feeding tube will be randomly assigned to one of the two…

This study tests whether daily supplements of lactoferrin and lysozyme, proteins found in milk, can prevent severe diarrhea and improve nutrition in children aged 6-24 months who were hospitalized with diarrhea and malnutrition. Six hundred children in Kenya will receive one of t…

This study is testing the safety of Omegaven, a fish oil-based fat emulsion, in 40 children under 18 who have developed liver problems (cholestasis) from long-term IV nutrition. The main goal is to see how many children develop essential fatty acid deficiency during at least 8 we…

This study is testing whether eating almonds can help heal broken thigh and shin bones as effectively as vitamin D supplements, but with fewer side effects and lower cost. The trial will include 136 adults with these fractures, who will receive either almonds, vitamin D, or both,…

This study tests a robot-assisted capsule (a pill-sized camera) to examine the stomach and small bowel in people with iron deficiency anaemia whose cause hasn't been found by standard tests. The goal is to see if this less invasive method works as well as traditional upper endosc…

This study looks at how to best provide multiple micronutrient supplements (MMS) to pregnant women through Uganda's health system. About 4,000 pregnant women will receive MMS in different bottle sizes to see which approach improves supplement use and clinic attendance. The goal i…

This study tests whether adding folic acid to iodized salt can raise folate levels in women of childbearing age in Zambia, a country without mandatory folic acid fortification. Two hundred fifty non-pregnant, non-lactating women aged 18–45 will use the fortified salt instead of r…

This study compares two different doses of vitamin D3 supplements in pregnant women who have low vitamin D levels. The goal is to see if a higher dose (50,000 IU every two weeks) is better than a lower dose (5,000 IU weekly) at preventing preeclampsia, a serious pregnancy complic…

This study compares two types of nutrient supplements—small-quantity and medium-quantity—to see if the smaller one works just as well at preventing undernutrition in children aged 6 to 12 months. About 980 infants in Pakistan will receive one of the two supplements daily for 6 mo…

This study in Chad and Niger tests whether giving a small, nutrient-packed food supplement (SQ-LNS) to children aged 6 to 11 months can encourage families to complete routine vaccinations. Around 20,000 children will receive the supplement until they are 18 months old, and resear…

This study tests whether a probiotic called LP299V can help pregnant women at risk of iron deficiency absorb more iron from their diet. Researchers will give 250 women either the probiotic or a placebo from early pregnancy until labor. The goal is to see if the probiotic improves…

This study tests whether a group program for newly married women, their husbands, and mothers-in-law can reduce anemia and improve nutrition. About 2,100 people in 140 villages will take part. The program includes education on nutrition and gender norms, plus micronutrient supple…

This study tests a family-based program using a mobile app to help prevent childhood obesity in school-age children (5-9 years old) in Sonora, Mexico. The program includes guidance on healthy eating, physical activity, and positive parenting. Researchers will compare families who…

This study looks at whether taking a daily iron supplement after sleeve gastrectomy surgery can prevent iron deficiency anemia. Researchers will compare two groups of adults who had the surgery: one group takes extra iron plus a multivitamin, the other takes only a multivitamin. …

This study tests whether taking vitamin D supplements can prevent preeclampsia from returning in pregnant women who had it before. About 146 women will be randomly assigned to take either vitamin D or a placebo pill until 36 weeks of pregnancy. Researchers will track blood pressu…

This study tests whether a gentle electrical stimulation on acupoints or resistance exercises can help raise hemoglobin levels in women with iron deficiency anemia. Sixty women aged 20-30 with moderate anemia will be split into three groups: one receiving the electrical stimulati…

This study tests if injecting vitamin C and glutathione into dark gums can lighten them as well as surgery. About 30 adults with gum pigmentation will be randomly assigned to either injection or scalpel removal. The main goal is to see how much the color improves, and the study a…

This study looks at whether taking lactoferrin (a protein found in milk) along with a small amount of iron can improve iron levels and exercise performance in active women who have low iron stores. About 30 women aged 18-45 who exercise at least 5 hours a week will take one of th…

This study is testing a program called MyCarePulse and ASCENT to help cancer patients overcome food-related challenges. About 100 adults recently diagnosed with certain cancers will either receive the program or standard care. The goal is to see if the program improves food secur…

This study tests whether a single dose of intravenous iron (ferric derisomaltose) can improve exercise capacity in people with heart failure with preserved ejection fraction who also have iron deficiency. About 66 adults will receive either the iron infusion or a placebo, and the…

This study is testing a mobile app called Diet4painrelief that helps people with chronic pain improve their eating habits. About 200 adults with chronic pain and a BMI of 25 or higher will take part. The goal is to see if the app can reduce pain, improve sleep, and make daily lif…

This study tests whether remote nutritional counseling helps cancer patients stick to their treatment plan and feel better. 240 adults with invasive cancer starting therapy will receive either a single consultation with written materials or a more intensive program with monthly f…

This study tests whether giving iron infusions after a minimally invasive heart valve replacement (TAVI) helps patients with aortic stenosis and iron deficiency feel better and walk farther. About 402 older adults will be randomly assigned to receive iron or standard care. Resear…

This Phase 2 trial is testing whether a daily supplement called Alii can reduce common side effects of hormonal birth control pills, like low energy, mood swings, and poor digestive health. Researchers will compare the supplement to a placebo in 68 women over 28 days. Participant…

This study tests whether a special protein drink called MediDrink Platinum+ can improve muscle strength, physical function, and overall well-being in adults aged 60 and older who have muscle loss (sarcopenia) and are malnourished. Participants will take the drink alone or with an…

This study tests whether serving food as easy-to-grip bites (finger food) helps elderly residents in care homes eat more, gain weight, and enjoy meals more. Thirty residents over 75 with weight loss or muscle loss will be randomly assigned to finger food or usual meals. The main …

This study tests whether taking vitamin K2 supplements daily for 6 months can reduce the number of migraine days in adults with episodic migraine. Researchers will also measure if it improves artery stiffness, which is often higher in people with migraines. 160 participants will …

This study tests whether a low dose of pancreatic enzymes (pancrelipase) taken with a nutritional supplement can help older adults at risk of malnutrition absorb nutrients better. Twenty hospitalized patients aged 70 or older will receive either the enzymes or a placebo alongside…

This study aims to learn more about methylmalonic acidemia (MMA) and related disorders by observing people with these conditions over time. Researchers will track complications, perform tests like blood draws and MRIs, and look for new genetic causes. The goal is to better unders…

This study looks at whether a woman's vitamin D level on the day of a frozen embryo transfer affects her chances of getting pregnant and having a baby. Researchers in the UAE will follow 126 women aged 18–40 undergoing frozen embryo transfer. The goal is to see if higher vitamin …

This study investigates whether a pregnant woman's body fat influences how well she responds to daily iron supplements. Over 300 pregnant women will take either 25 mg or 50 mg of iron each day from week 12 until delivery. Researchers will track iron levels in blood and other heal…

This study investigates whether older adults with age-related hearing loss (presbycusis) can still hear and enjoy the sound of a crunchy biscuit while eating. Researchers will compare a crunchy biscuit with a soft one in 100 seniors aged 65 and older, asking them if they hear the…

This study is looking at whether people with a common inner-ear condition called benign paroxysmal positional vertigo (BPPV) have lower vitamin D levels than those without it. Researchers will compare vitamin D in 160 adults — half with BPPV and half without. The goal is to see i…

This study is testing whether giving elderly patients with a broken hip and high frailty a special nutritional drink before surgery can help them stay more stable during the operation and recover better. Researchers will compare patients who get the drink with those who follow st…

This study surveys 150 women aged 18-64 who follow vegetarian or vegan diets to assess their nutritional quality and adequacy. Participants will receive personalized nutritional counseling based on blood tests and food diaries. The goal is to see if counseling can improve diet, b…

This study is testing whether giving monthly food vouchers to low-income households in the Philippines, along with nutrition classes, can reduce hunger and improve diet quality. About 5,320 families will be split into groups receiving different voucher amounts or no voucher. Rese…

This study gives 200 athletes either high-dose vitamin D3 (4,000 IU daily) or a placebo for 4 to 8 weeks. Researchers measure changes in vitamin D levels, hormones, muscle function, cognitive performance, and body composition. The goal is to see if extra vitamin D improves athlet…

This study looks at how low vitamin D levels affect balance and the way muscles respond to movement. Researchers will compare adults with vitamin D deficiency to healthy adults using simple standing tests and muscle sensors. No treatments or blood draws are involved—just one sess…

This study tests whether an AI system that analyzes routine blood test results can help doctors detect iron deficiency more often. About 2,196 adults visiting outpatient clinics will take part, but no extra blood draws or procedures are needed—the AI simply adds a risk alert to t…

This study looks at whether a special type of high-intensity interval training can help overweight adults maintain healthy vitamin D levels during winter. Thirty participants will either exercise three times a week for 12 weeks or just follow a balanced diet. Researchers will mea…

This study looks at whether giving extra nutrition through a feeding tube before surgery can lower the chance of complications in malnourished people with esophageal or stomach cancer. About 670 participants will be followed to compare those who get nutritional support with those…

This study uses MRI scans to track where iron travels in the body after an intravenous iron infusion. Researchers will monitor 12 iron-deficient adults over hours, days, and weeks to see how iron is absorbed by organs like the heart, liver, and spleen. The goal is to better under…

This study tests whether offering a small cash payment to households can encourage more people to get screened for tuberculosis (TB) in rural Tanzania. Researchers will enroll 360 people recently diagnosed with TB and their families. Half will receive the usual care, and half wil…

This study looks at new guidelines for diagnosing and managing breath-holding spells in children under 5 in southern Sweden. Researchers want to see if the guidelines safely reduce the need for extra tests like ECGs and blood work. They will also check if iron supplements help le…

This study looks at how common muscle loss and weakness are in people with liver cirrhosis, and how malnutrition plays a role. Researchers will use ultrasound to measure muscle size and a grip test to check strength. The goal is to better understand the problem and its impact on …

This study is checking if a 7-year program by World Vision helps improve nutrition, gender equality, and health access for women, teenage girls, and young children in rural areas of Bangladesh, Kenya, and Tanzania. About 13,500 people will take part, including women, their partne…

This study looks at how much iron healthy US adults actually need. Current guidelines are based mostly on European data, so researchers want to update them for Americans. About 300 men and premenopausal women aged 18–50 will take a safe, stable iron isotope and give blood samples…

This study compares two forms of iron (ferrous fumarate and ferrous bisglycinate) in daily prenatal supplements for 172 pregnant women in Vancouver. Researchers will measure iron levels in blood and stool samples to see which form is better absorbed and causes fewer side effects.…

This study looks at whether low magnesium in the blood is linked to memory, attention, and other thinking problems after a stroke. Researchers will measure magnesium levels and give cognitive tests to 80 stroke patients over several weeks. The goal is to understand if magnesium d…

This study looks at how different types and doses of oral iron supplements affect iron levels, exercise performance, and gut health in young female athletes with low iron stores. Participants will take one of three iron supplements every other day for 12 weeks and complete fitnes…

This study looks at medical records of 1000 children with conditions like autism, epilepsy, and Down syndrome to find common biological patterns. Researchers want to understand what causes these disorders and how children respond to treatments. The goal is to improve diagnosis an…

This study will follow 1,000 adults who are taking vitamin D supplements for low vitamin D levels. Researchers will collect health data over 10 years to see how vitamin D use relates to conditions like heart disease, diabetes, cancer, and osteoporosis. The goal is to learn more a…

This study follows 142 adults having lung cancer surgery to see if measuring nutrition and muscle loss can help predict complications, hospital stay, and survival. Participants get blood tests, CT scans, and ultrasound before surgery. The goal is to create a better risk score to …

This study is for older adults, including those in the hospital or with low priority care needs. Researchers want to see if newer methods, like body scans and blood tests, can better detect malnutrition and kidney problems than current standard tests. The goal is to make diagnosi…

This study tests a goat milk-based formula alternative (GMDFA) in 15 infants aged 8-10 weeks who cannot exclusively breastfeed. Researchers compare growth, gut health, and nutrition markers between infants fed GMDFA, undiluted goat milk, or breast milk. The goal is to see if GMDF…

This study looks at whether the amount of vitamin D in your blood affects your chance of developing thyroid problems while receiving immunotherapy for cancer. Researchers will measure vitamin D and thyroid function before and during standard cancer treatment. The goal is to see i…

This study looks at how well young women with overweight or obesity absorb iron from their diet compared to women at a healthy weight. Researchers will track iron levels and losses over time in 70 South African women. The goal is to understand why obesity raises the risk of iron …

This study tests a new, radiation-free ultrasound technology called REMS to measure bone density in children aged 5 to 18 who have conditions that weaken bones, such as brittle bone disease or osteoporosis. The goal is to see if REMS can work as well as the standard X-ray method …

This study tests whether giving extra arginine (a nutrient) to preterm and full-term infants after major bowel surgery or a serious gut infection (necrotising enterocolitis) can improve their immune function. Researchers will measure changes in gene activity related to infection-…

This study looks at how nutrition and body composition (like muscle and fat) impact the health of people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 300 participants starting new medical treatments or having sur…

This study tests a mobile health app called First Diet to help new mothers in Pakistan improve breastfeeding and feeding practices for their infants. Researchers will enroll 300 pregnant women who have smartphones and follow them for one year after birth. The goal is to see if th…

This study looks at whether wrapping lactoferrin, a natural protein in milk, in a protective coating helps women with low iron absorb more iron from their food. Forty-five women with low iron stores but no anemia will eat labeled iron with different forms of lactoferrin. Research…

This study tracks 300 adults who developed a surgical site infection after orthopedic surgery on their limbs or spine. Researchers will use questionnaires to measure how often depression and malnutrition occur over one year. The goal is to better understand these complications so…

This study tests whether a leadership program called LOCI helps nurses and their managers use the latest research in everyday care. About 300 nurses and managers from psychiatric and elder care units in Finland will take part. The program includes training and mentoring to improv…

This study aims to find out how common malnutrition and muscle loss (sarcopenia) are among adults visiting hospital clinics in Turkey. Researchers will screen 7,500 people aged 18 and older using questionnaires and simple physical tests like grip strength and calf measurement. No…

This observational study follows 334 adults with type 2 diabetes or drug-induced diabetes who are malnourished or at risk. Researchers will track their nutritional treatment patterns after being prescribed a special high-calorie, high-protein supplement with fiber. Participants f…

This study looks at whether the ammonia in your breath can help detect malnutrition. Researchers will take breath and blood samples from 12 adults, some with and some without malnutrition, and compare the results. A small group will also drink special beverages and fast for two d…

This study tests a community-based program to reduce child malnutrition in Punjab, Pakistan. About 200 children aged 7-15 months and their mothers will take part in a 28-day behavior change program that includes daily group sessions and home visits. The program teaches practical …

This study aims to understand what causes Visual Snow Syndrome (VSS), a condition where people see constant flickering dots across their vision. Researchers will use brain scans and visual tests to find which brain pathways are involved. About 100 adults with VSS, migraine, or he…

This study from Aarhus University is looking at how common magnesium deficiency is in people with Crohn's disease, ulcerative colitis, ileostomy, or bile acid diarrhea. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. T…

This study aims to find out how common malnutrition is among hospital patients in China, Europe, and the USA. It will also look at whether providing nutrition support to those at risk improves their health outcomes and is cost-effective. Researchers plan to enroll 2,000 patients …

This study is checking if pregnant women with low vitamin D are more likely to have a dangerous drop in blood pressure during a C-section when they get spinal anesthesia. Researchers will measure vitamin D levels before surgery and watch blood pressure closely during the procedur…

This study looks at how well malnourished children absorb iron from ready-to-use therapeutic foods. Researchers will compare healthy children with those who have acute malnutrition to see if too much iron causes problems like diarrhea. The goal is to make a safer, more effective …

This study looks at whether malnutrition changes how well older adults recover after shoulder surgery when they use virtual reality (VR) for rehabilitation. Researchers will track 60 frail adults aged 60+ to see if poor nutrition limits the benefits of VR therapy. The goal is to …

This study looks at how different forms of vitamin D work in the body. Researchers will measure free vitamin D (the active form) in healthy adults, pregnant women, and people with hormone or kidney problems. The goal is to see if free vitamin D gives a more accurate picture of vi…

This study is observing 1000 adults having moderate- to high-risk surgery to see if the type and severity of anemia they have before surgery affects their risk of complications like heart injury, kidney injury, or stroke. Researchers will compare patients with iron-deficiency ane…

This study is testing whether a special nutrition shake (Ensure Surgery Immunonutrition) can improve gut health and reduce inflammation in heart failure patients awaiting LVAD surgery. Researchers will give the shake to 50 hospitalized patients before their operation and track ch…

This study looks at whether patients in the ICU who need a tracheostomy can keep getting nutrition through a tube right up until surgery, instead of stopping 6 hours before. The goal is to see if this helps them get more food without increasing the risk of food getting into the l…

This study looks at how taking vitamin D3 and K2 supplements for 90 days changes blood levels and the community of bacteria in the gut (the microbiome) in healthcare workers with low vitamin D. About 96 participants will take either a vitamin D3, K2, both, or a placebo pill. Rese…

This study follows 368 mothers and their babies in Zimbabwe from pregnancy until the child turns 3. Researchers want to understand how malnutrition, poor water and sanitation, and gut problems affect child growth, infections, and development. They will measure gut bacteria, immun…

This study tests whether a plant-based, protein-dense sauce (ProSauce) helps older adults absorb essential amino acids better than a standard low-protein sauce, without making them feel too full. Twenty healthy adults aged 60 and over will eat two test meals in random order, and …

This study follows 48 adults with active Crohn's disease or ulcerative colitis who are starting biologic or JAK inhibitor therapy. Researchers use a quick, painless bioelectrical impedance scan to measure muscle mass and other body composition changes at the start, 24 weeks, and …

This study looks at how much protein cancer patients eat before, during, and after radiotherapy, and whether that affects their muscle mass and quality of life. Researchers will track 175 adults aged 45 and older undergoing radiation for various tumors. The goal is to understand …

This study is looking at 100 children aged 3 to 15 who have had a low-energy fracture (like a fall from standing height). Researchers want to see if vitamin D levels, bone markers, and weight are linked to fracture risk. They will compare children with fractures to those without.…