Could a single dose of azithromycin save more malnourished kids?

NCT ID NCT06010719

Recruiting now Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single dose of azithromycin helps children aged 6-59 months with severe acute malnutrition gain weight better than the standard 7-day amoxicillin course or a placebo. Researchers will enroll 3,000 children in Burkina Faso and track weight gain and nutritional recovery over 8 weeks. The goal is to find a more effective antibiotic to reduce deaths in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: azithromycin
What this could lead to: If it works, this could offer a simpler, more effective antibiotic option to help malnourished children recover and reduce mortality.
What could go wrong: This is a Phase 4 trial, but previous studies on antibiotics for malnutrition have had conflicting results, so azithromycin may not prove better than current care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Child Nutrition Disorders nutritional deficiency disease protein-energy malnutrition Severe Acute Malnutrition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALNUTRITION, CHILD SEVERE ACUTE MALNUTRITION

Contacts and locations

Locations

Centre de recherche en Santé de nouna
RECRUITING

Nouna, Kossi, Burkina Faso

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