Can a better diet during malnutrition recovery rewire a Child's brain?

NCT ID NCT05629624

Completed Disease control Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study looks at whether specially designed nutritional supplements can improve thinking skills and emotional control in young children in Bangladesh who have moderate malnutrition. About 300 children aged 1 to 3 years receive either standard or enhanced nutritional supplements along with a psychosocial stimulation program. Researchers measure changes in brain activity and development using tests and brain imaging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: special nutritional supplements (E-RUSF and E-SQLNS) plus psychosocial stimulation
What this could lead to: If successful, this could show that targeted nutrition during early childhood recovery from malnutrition can improve brain development and emotional regulation.
What could go wrong: This is a small pilot study, so results may not apply broadly. The supplements may not outperform standard feeds, and long-term benefits remain uncertain.

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Conditions

The condition(s) this trial relates to.

Child Nutrition Disorders Emotional Regulation Malnutrition nutritional deficiency disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMOTIONAL REGULATION EXECUTIVE FUNCTION DISORDER MALNUTRITION, CHILD

Contacts and locations

Locations

International Centre for Diarrheal Disease Research

Dhaka, Bangladesh

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