Could a vitamin d boost strengthen bones and mobility after neurological injury?

NCT ID NCT06791044

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This trial is testing whether vitamin D supplements can improve bone density, body composition, strength, walking speed, and physical performance in people hospitalized with neurological disorders like stroke, spinal cord injury, or traumatic brain injury. Participants will receive one of two vitamin D dosing plans over 8 weeks, while researchers track changes in these health measures and pain levels. The study also includes healthy controls for comparison, aiming to understand how common vitamin D insufficiency is in this population and whether supplementation helps.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Vitamin D (cholecalciferol) supplements at two dosing schedules
What this could lead to
If vitamin D supplementation improves bone density, strength, and physical performance in people with neurological disabilities, it could point to a simple, low-cost way to enhance their quality of life and reduce fracture risk.
What could go wrong
This is a relatively small trial, and results may not apply to all neurological patients. Vitamin D may not significantly improve the measured outcomes, and high doses could carry risks like elevated calcium levels.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Rehabilitation Center EKA

    RECRUITING

    Nea Liosia, Athens, 13122, Greece

  • National Rehabilitation Center EKA (Ethniko Kentro Apokatastasis)

    RECRUITING

    Athens, Attica, 13122, Greece

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