Vitamin d trial hopes to ease PCOS symptoms in teen girls

NCT ID NCT04355572

Recruiting now Disease control Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking vitamin D daily for 6 months can improve menstrual regularity and mood in teenage girls with PCOS who also have low vitamin D levels. Sixty participants will be randomly assigned to receive either vitamin D or a placebo, and neither they nor their doctors will know which group they are in. The goal is to see if this simple supplement can help manage PCOS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D (4000 IU daily)
What this could lead to: If it works, this could point toward a simple, low-cost way to improve menstrual cycles and well-being in teens with PCOS.
What could go wrong: This is a small, early-stage trial with only 60 participants. The results may not apply to all teens with PCOS, and vitamin D may not significantly improve symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYSTIC OVARIAN SYNDROME IN ADOLESCENT FEMALES VITAMIN D DEFICIENCY

Contacts and locations

Locations

Yale New Haven Children's Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

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