Vitamin d trial hopes to ease PCOS symptoms in teen girls

NCT ID NCT04355572

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This study tests whether taking vitamin D daily for 6 months can improve menstrual regularity and mood in teenage girls with PCOS who also have low vitamin D levels. Sixty participants will be randomly assigned to receive either vitamin D or a placebo, and neither they nor their doctors will know which group they are in. The goal is to see if this simple supplement can help manage PCOS symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale New Haven Children's Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin D (4000 IU daily)

What this could lead to

If it works, this could point toward a simple, low-cost way to improve menstrual cycles and well-being in teens with PCOS.

What could go wrong

This is a small, early-stage trial with only 60 participants. The results may not apply to all teens with PCOS, and vitamin D may not significantly improve symptoms.

Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.